OVERVIEW

The 9th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) is organized by CME Congresses Ltd and will be held from Oct 24 - 27, 2024 at Hotel nhow Berlin, Berlin, Berlin, Germany.

Description:
The COSTEM Congress is a platform for our community to interact with each other and to share our scientific research, clinical experience, and on-going developments in our field. COSTEM encourages active participation in debate discussions and challenges global experts to promote their positions on a wide range of burning issues – providing clinicians the opportunity to share, express and compare experiences in order to establish and advance effective and reliable patient treatments.

COSTEM 2024 will continue to push the envelope and be a progressive, compelling and informative congress, where the most compelling and controversial topics facing clinicians in our field are presented in a fascinating and exciting debate forum.

Main Topics:
• Acute leukemia
• Bi-specific antibodies
• CMV infection
• CAR T-cell therapy and cellular therapy
• Cord blood transplantation
• Donor lymphocyte infusion
• Drug conjugated antibodies
• Genome editing and gene therapy
• GvHD prevention and treatment
• Haploidentical stem cell transplantation
• Hodgkin and Non-Hodgkin lymphoma
• Mesenchymal stem cell
• Multiple myeloma
• Myeloproliferative neoplasm
• Myelodysplastic syndrome
• NK Cell therapy
• Pediatric indications for transplantation
• Relapse prevention
• Toxicity post transplantation (VOD, TMA, etc.)
• Transplant for severe aplastic anemia and hemoglobinopathies
• Virus specific T Cell therapy

Scientific Program:

Thursday, October 24
17:15-17:45Industry-supported Meet the Expert Session 
17:45-18:00Technical Break
18:00-18:30ECP and Ruxolitinib combination in severe steroid-refractory acute GvHD
Industry-supported Meet the Expert Session 
Friday, October 25
08:00-08:15Good Morning Coffee
08:15-08:30Welcome Note
Congress Co-Chairs
08:30-10:00Session 1: Graft-versus-host disease (GvHD) Prophylaxis and Treatment
 Controversy: Is Post-transplant cyclophosphamide (PTCy) or anti-thymocyte globulin (ATG) the current standard for GvHD prophylaxis in matched unrelated transplant?
 Moderator: Nicolaus Kröger, Germany
08:30-08:45PTCy: Leo Luznik, USA
08:45-09:00ATG: Takanori Teshima, Japan
 Controversy: Is Axatilimab becoming the new standard for chronic cGvHD?
 Moderator: Arnon Nagler, Israel
09:00-09:15Yes: Stephanie Lee, USA
09:15-09:30No: Corey Cutler, USA
09:30-10:00Panel discussion: All session faculty
10:00-10:20Coffee Break, Poster Viewing and Visit Exhibition
10:20-11:50Industry-supported Symposium
11:50-12:00Technical Break
12:00-13:30Session 2: Acute Myeloid Leukemia (AML)
 Controversy: Should 5-Azacitidine venetoclax-based induction replace 7+3 induction in AML 50-65 years of age?
 Moderator: Andreas Burchert, Germany
12:00-12:15Yes: Thomas Schroeder, Germany
12:15-12:30No: Lars Bullinger, Germany
 Controversy: Should all FMS?like tyrosine kinase 3 (FLT3)-positive AML receive maintenance therapy post-allograft?
 Moderator: Lars Bullinger, Germany
12:30-12:45Yes: Andreas Burchert, Germany
12:45-13:00No: Arnon Nagler, Israel
13:00-13:30Panel discussion: All session faculty
13:30-14:15Lunch Pick-up, Poster Viewing and Visit Exhibition
14:15-15:15Industry-supported Lunch Symposium
15:15-15:30Short Break
15:30-17:00Session 3: Acute Lymphoblastic Leukemia (ALL)
 Controversy: Should we include short-course blinatumomab in adult ALL patients with minimal residual disease (MRD) pre allogeneic stem cell transplantation (allo-SCT)?
 Moderator: Matthias Stelljes, Germany
15:30-15:45Yes: Nicola Gökbuget, Germany
15:45-16:00No: Sebastian Giebel, Poland
 Controversy: Are we ready for total body irradiation (TBI)-free conditioning in adult ALL
 Moderator: Sebastian Giebel, Poland
16:00-16:15Yes: Avichai Shimoni, Israel
16:15-16:30No: Matthias Stelljes, Germany
16:30-17:00Panel discussion: All session faculty
17:00-17:30Coffee Break, Poster Viewing and Visit Exhibition
17:30-19:00Session 4: Myelodysplastic Syndromes (MDS) and Myeloproliferative Neoplasms (MPN)
 Controversy: Are we ready for molecular prognostication for transplant decision making in MDS?
 Moderator: Nicolaus Kröger, Germany
17:30-17:45Yes: Carmelo Gurnari, Italy
17:45-18:00No: Fernando Barroso Duarte, Brazil
 Controversy: Are we ready for molecular prognostication for transplant decision making in MPN?
 Moderator: Avichai Shimoni, Israel
18:00-18:15Yes: Nico Gagelmann, Germany
18:15-18:30No: Donal McLornan, UK
18:30-19:00Panel discussion: All session faculty
Saturday, October 26
08:30-10:00Session 5: Lymphoma and Myeloma
 Controversy: Can we replace autologous stem-cell transplantation (auto-SCT) for multiple myeloma by CAR T or bispecific antibodies?
 Moderator: Claudio Cerchione, Italy
08:30-08:45Yes: TBA
08:45-09:00No: Maximilian Merz, Germany
 Controversy: Do we abandon allo-SCT for Non-Hodgkin’s lymphoma?
 Moderator: Nico Gagelmann, Germany
09:00-09:15Yes: Anna Sureda, Spain
09:15-09:30No: Ali Bazarbachi, Lebanon
09:30-10:00Panel discussion: All session faculty
10:00-10:30Coffee Break, Poster Viewing and Visit Exhibition
10:30-12:00Session 6: GvHD Prevention and Treatment
 Controversy: Is abatacept the new standard for matched and mismatched unrelated donor SCT?
 Moderator: Corey Cutler, USA
10:30-10:45Yes: Robert Soiffer, USA
10:45-11:00No: Francesca Bonifazi, Italy
 Controversy: Are mesenchymal stem cells (MSC) an alternative to ruxolitinib in SR GvHD?
 
 Moderator: Francis Ayuk, Germany
11:00-11:15Yes: Peter Bader, Germany
11:15-11:30No: Hildegard Greinix, Austria
11:30-12:00Panel discussion: All session faculty
12:00-12:45Lunch Pick-up, Poster Viewing and Visit Exhibition
12:45-14:15Industry-supported Lunch Symposium
14:15-14:30Short Break
14:30-16:00Session 7: Non-malignancies
 Controversy: Are we ready for haploidentical stem cell transplantation (haplo-SCT) upfront as routine practice in severe aplastic anemia (SAA)?
 Moderator: Emanuele Angelucci, Italy
14:30-14:45Yes: Carlo Dufour, Italy
14:45-15:00No: Antonio Risitano, Italy
 Controversy: Haplo-SCT vs gene therapy in sickle cell disease (SCD)
 Moderator: Franco Locatelli, Italy
15:00-15:15Haplo-SCT: Emanuele Angelucci, Italy
15:15-15:30Gene therapy: Markus Mapara, USA
15:30-16:00Panel discussion: All session faculty
16:00-16:30Coffee Break, Poster Viewing and Visit Exhibition
16:30-17:30Session 8: Myths and Facts around EBV post HSCT
 A series of statements and disucssion
Moderator: Jan Styczynski, Poland
16:30-16:40Statement: There is a threshold for EBV PCR in blood starting treatment with Anti CD20 antibodies
Facts, presented by: Marcos de Lima, USA
16:40-16:50Statement: EBV specific T cells are the treatment of choice for EBV reactivation and EBV related PTLD
Facts, presented by: Guenther Koehne, USA
16:50-17:00Statement: EBV serostatus predicts outcome after allogeneic HSCT
Facts, presented by: Jan Styczynski, Poland
17:00-17:30Panel discussion: All session faculty
17:30-17:45Short Break
17:45-19:15Session 9: Pediatrics
 Controversy: Do we need allogeneic HSCT consolidation after CD19 CAR T therapy for pediatric ALL?
 
 Moderator: Krzysztof Kalwak, Poland
17:45-18:00Yes: Peihua Lu, China
18:00-18:15No: André Baruchel, France
 Controversy: ?? T cells T cell depletion Haplo-SCT vs non T cell depletion Haplo-SCT in pediatric malignancies
 Moderator: Emanuele Angelucci, Italy
18:15-18:30?? T cells T cell depletion: Franco Locatelli, Italy
18:30-18:45Non T cell depletion: Krzysztof Kalwak, Poland
18:45-19:15Panel discussion: All session faculty
19:15Poster Walk and Awards Session
(Poster Area)
Sunday, October 27
09:00-10:30Session 10: Artificial Intelligence (AI) and Specific Cell Therapy
 Controversy: Are we ready for prediction of transplant-related complication including GvHD by machine-learning and AI?
 
 Moderator: Alessandro Rambaldi, Italy
09:00-09:15Yes: Roni Shouval, USA
09:15-09:30No: Francis Ayuk, Germany
09:30-09:45Discussion
 Controversy: Will cytotoxic T lymphocytes (CTL)s become a standard option for post-transplant infection?
 
 Moderator: Lori Muffly, USA
09:45-10:00Yes: Britta Eiz-Vesper, Germany
10:00-10:15No: Rafael de la Cámara, Spain
10:15-10:30Discussion
10:30-11:00Coffee Break
11:00-12:30Session 11: Graft Manipulation and Autoimmune Diseases
 Controversy: Are we back to graft manipulation in allogeneic transplantation?
 
 Moderator: Nicolaus Kröger, Germany
11:00-11:15Yes: Lori Muffly, USA
11:15-11:30No: Alessandro Rambaldi, Italy
11:30-11:45Discussion
 Controversy: Do CAR T cells replace autologous SCT in autoimmune disease?
 
 Moderator: Arnon Nagler, Israel
11:45-12:00Yes: Fabian Müller, Germany
12:00-12:15No: Raffaella Greco, Italy
12:15-12:30Discussion
12:30Closing remarks
Congress Co-Chairs

KEY DATES

Event Start Date
24 Oct, 2024
Event Start Date
Event End Date
27 Oct, 2024
Event End Date
Credits

EBAH CME Accreditation:
The EBAH- CME Unit has approved this educational activity for a maximum number of CME credits. Each physician should only claim credits for time that she/he actually spent in the educational activity. We are pleased to inform you that the 2024 COSTEM Congress has been awarded:

  • 13.5 EBAH-CME Credit Points

All participants may print a European Board for Accreditation in Hematology (EBAH) CME certificate indicating the number of EBAH-CME Credit Points awarded, directly from the system on the CME section of the EBAH website.

AEKB CME Accreditation:
The 9th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) has been accredited by the Berlin Chamber of Physicians (Ärzetkammer Berlin) for a maximum of 

  • 12 CME credits


Day 1 (October 25): 6 CME credits, Category B

Day 2 (October 26): 6 CME credits, Category B

Each medical specialist should claim only those days of credit that they actually spent in the educational activity. The Berlin Chamber of Physicians’ CMEC credit system is based on 1 CMEC per 45 minutes.

  • 13.5 CME
  • SPEAKERS

    TARGET AUDIENCE

    PhysicianScientistsStudentsOncologistsResidentsNursesHematologistTrainees

    SPECIALITIES

    HaematologyCell and Developmental BiologyHematology Blood and Marrow TransplantPediatric Hematology and Bone Marrow TransplantOncology

    SUGGESTED HOTELS

    CONFERENCE VENUE

    LocationHotel nhow Berlin
    Stralauer Allee 3

    CANCELLATION & REFUND POLICY

    Cancellation Policy:
    All cancellations must be faxed, electronically mailed or postmarked. Refund of registration fees will be as follows:

    Postmarked up until September 1, 2024 – 100% refund (minus € 50 handling fee and bank charges)

    Postmarked from September 2, 2024 – 50% refund

    No refund on cancellations sent after October 10, 2024

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