5th Annual Internal Medicine in Primary Care Conference is organized by Continuing Education Company, Inc. (CEC) and will be held from Jul 30 - Aug 06, 2021 at Celebrity Solstice Alaska Cruise, Seattle, Washington, United States of America. Target Audience: This course is intended for Family Practice, Internal Medicine, Nurse Practitioners, Physician Assistants and other Health Care Professionals. Accreditation: AAFP: This live activity, 5th Annual Internal Medicine in Primary Care Conference, with a beginning date of July 30, 2021 has been reviewed and is acceptable for up to 20.00 Prescribed credit(s) by the American Academy of Family Physicians. AMA PRA Category 1 Credit ™: Continuing Education Company designates this live activity for a maximum of 20 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. ABIM MOC: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 20 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. CFPC: Members of the College of Family Physicians of Canada are eligible to receive 20 MAINPRO-M1 credits for participation in this activity due to reciprocal agreement with the American Academy of Family Physicians. Overview: Continuing Education Company has been organizing its Primary Care Conference Series for over 29 years. The 5th Annual Internal Medicine in Primary Care Conference is designed to update primary care clinicians in rapidly changing therapeutic areas. The emphasis is on practical and useful information for clinical practice. Join us July 30 through August 6, 2021 when we host the 5th Annual Internal Medicine in Primary Care Conference on the Celebrity Solstice while cruising Alaska and British Columbia. Program Objectives: As a result of this conference, participants will be able to: • Assess and provide patients with an accurate diagnosis and optimal care for a broad range of disorders seen in primary care. • Utilize current guidelines in the diagnosis and management of commonly encountered therapeutic issues. • Formulate comprehensive evidence-based interventions and treatment strategies that will lead to the reduction of modifiable risk factors and improved long term outcomes. Celebrity Solstice Alaska Cruise: Alaska Inside Passage, Tracy Arms Fjords & Glacier, Juneau, Ketchikan, Skagway, and Victoria, BC (leaving from Seattle, WA) FREE 15 credit online course for all live meeting attendees   Additional details will be posted as soon as information is available.

Emergency Medicine Conference is organized by Continuing Education, Inc. and will be held from Apr 03 - 10, 2021 at Royal Caribbean's Symphony of the Seas, Miami, Florida, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners, Pharmacists Accreditation: • 14 AMA PRA Category 1 Credits™ • 14 ACPE Credits • 14.0 Contact Hours  Additional details will be posted as soon as information is available.

Internal Medicine, Critical Care, and Hospital Medicine is organized by Continuing Education, Inc. and will be held from Apr 11 - 18, 2021 at Royal Caribbean's Allure of the Seas, Miami, Florida, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners, Pharmacists Accreditation: • 14 AMA PRA Category 1 Credits™ • 14 ACPE Credits • 14 (part II) MOC points in medical knowledge in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program • 14.0 Contact Hours Description: This educational series will present attendees with key updates in clinical topics fundamental to the care of the adult inpatient, including major advances from the medical literature. Additionally, this educational series will review fundamental skills basic to the practice of hospital medicine, such as diagnostic test interpretation and medical decision making. Hospital medicine is a 'team sport' with a wide breadth of content, and this educational series will help attendees provide the most advanced hospital medicine care and allow them to bring what they learn back to their home institutions and share with their teams. Topics: • Hospital Medicine Literature Highlights - Cardiology, Cancer, Nephrology ○ Upon completion of this activity, attendees should be able to describe key updates & current literature related to the modern practice of hospital medicine. • Hospital Medicine Literature Highlights 2- Infectious Disease, Pulmonary Disease, Rheumatology ○ Upon completion of this activity, attendees should be able to describe key updates & current literature related to the modern practice of hospital medicine. • Tick Borne Diseases ○ Upon completion of this activity, attendees should be able to recognize key clinical features of tick borne diseases. • Test Interpretation and Medical Decision Making ○ Upon completion of this activity, attendees should be able to interpret medical test results in a scientific manner. • Venous Thrombosis and Pulmonary Embolism - prophylaxis and treatment ○ Upon completion of this activity, attendees should be able to describe the current standard of care for prophylaxis and treatment of venous thrombosis in a hospitalized patient. • Special Considerations for the Geriatric Patient ○ Upon completion of this activity, attendees should be able to describe key treatment considerations for geriatric inpatients. • Sepsis and Shock ○ Upon completion of this activity, attendees should be able to describe the current state of sepsis recognition and treatment, in accordance with widely accepted published guidelines. Conference Sessions generally take place on days at sea (as itinerary allows), giving you plenty of time to enjoy your meals, evenings and ports of call with your companion, family and friends.

Emergency Medicine, Violence Against Women, and Physician Wellness is organized by Continuing Education, Inc. and will be held from Apr 18 - 25, 2021 at Royal Caribbean's Allure of the Seas, Miami, Florida, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners, Pharmacists Accreditation: • 14 AMA PRA Category 1 Credits™ • 14 ACPE Credits • 14.0 Contact Hours Description: These lectures provide a framework and outline processes for the emergency department health care team to manage challenging encounters, address workplace violence, and to improve provider wellbeing. Additionally, the lectures incorporate materials with the goal of participants forming a multidisciplinary team to respond effectively in caring for patients suffering from intimate partner violence and sexual assault. Topics: • Workplace violence ◘ Create a plan to apply the principals of de-escalation and safe contingency plans when confronting a potentially violent patient. • Intimate Partner Violence ◘ Employ the principals of identification, treatment, documentation and referral to aid patients suffering from intimate partner violence • Sexual Assault ◘ Determine which patients have suffered the consequences of sexual assault and how to manage the encounter with compassion. • Physician Burnout and Depression ◘ Cite the causes of burnout and depression in physicians. • Improving Provider well-being Personal and Institutional Interventions ◘ Devise a plan for personal and institutional wellness at work. • Challenging Interactions in the Medical Setting ◘ Assess what makes an interaction challenging and plan optimal ways to meet those challenges. • The Silent Killers: 8 common medications that could kill your patient ◘ Identify 8 medications with serious side effects that may harm our patients.  Conference Sessions generally take place on days at sea (as itinerary allows), giving you plenty of time to enjoy your meals, evenings and ports of call with your companion, family and friends.  Additional details will be posted as soon as information is available.

Pulmonary and Critical Care Medicine, Women's Health, and Domestic Violence is organized by Continuing Education, Inc. and will be held from Apr 24 - May 01, 2021, Celebrity Apex, Fort Lauderdale, Florida, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners, Pharmacists, Psychologists, Social Workers. Accreditation: • 14 AMA PRA Category 1 Credits™ • 14 ACPE Credits • 14 CE Credits for Psychologists • 14 ASWB ACE Credits • 14.0 Contact Hours Additional details will be posted as soon as information is available.

Treating Your Peri-menopause and Menopausal patient: Symptoms, Sex and Health Promotion; Women's Health, Phlebology Course is organized by Continuing Education, Inc. and will be held from Feb 20 - 27, 2021 at Holland America's Koningsdam, San Diego, California, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners, Pharmacists Accrteditation: • 14 AMA PRA Category 1 Credits™ • 14 ACPE Credits • 14.0 Contact Hours Program Purpose: Primary Care Physicians are dedicated to taking care of a wide variety of medical conditions and must also be dedicated to life long learning. Our approach must constantly evolve to keep up with the changes in available treatments, new research, reimbursement models, government regulation and electronic medical record requirements. This series of lectures serves to review and update PCPs on common conditions we see in the office everyday using available new guidelines (such as Diabetes and Hypertension) as well as what is new within the field of Family Medicine (such as the latest on immunizations and primary care research). Many changes have taken place in the field of women's physical and emotional health creating significant implications for those who care for female patients. This program is designed to provide participants with current up to date information in order to provide the very best in contemporary patient care. Unique to the lecture format is the identification and analysis of specific physical disorders and their effect on the emotional health of patients. Participants should be able to apply this new knowledge immediately into clinical practice. A multi-discipline, integrated approach to patient care is emphasized with an eye towards quality improvement and overall health care team performance. Topics: • Hot Topics in Menopause/Perimenopause 2021 ○ Understand the most recent topics in the care of peri - and post-menopausal women • Evidence based Hormone Replacement Therapy ○ Review the older and more recent studies on menopausal hormone replacement regarding treatment plans and safety. • Hyposexual Desire Disorder ○ Identify this condition and utilize a simple screening tool for diagnosis; become familiar with treatment plans and their ability to relieve HSDD successfully • Genitourinary Syndrome of Menopause ○ To identify the components of this condition ○ To comfortably discuss the syndrome and have a comprehensive list of treatment options based on individual desire and need. • Care of Peri-Menopausal Patient ○ Recognize that the period of Peri-menopause has very specific physical, emotional and hormonal symptoms associated with it ○ Define these and offer specific treatment options for this time period • Mood disorders in Menopause ○ Realize that mood disordes like anxiety and depression may present or worsen in the menopausal time period, and have a method for identifying these and effectively treating them. • Breast density- what does it mean? ○ To label the various categories of breast density and to become familiar witha algorithms that identify increased breast cancer risk . • Chronic Venous Insufficiency ○ Appropriate diagnostic approaches to evaluate and treat patient accross the entire spectrum CVI. • Pelvic Phlebology ○ Identify causes and sequelae of CVI unique to the pelvic anatomy in female patients. • Pelvic Pain/Endometriosis ○ Analize pelvic pain in the clinical setting of endometriosis and differentiate between dysmenorrhea, non-menstrual pelvic pain and pain with intercourse. • Androgen Excess- Physical bother vs. Emotional burden ○ Develop a cost-effective thorough plan for assessing PCOS and its sequelae in patients who do and do not want to conceive. • Vaginitis revisited ○ Identify routine as well as challenging causes of vulvar symptoms of burning, itching or pain. Expand upon vaginitis related to estrogen deprivation. • Menopause, Memory Loss and Dementia ○ Recognize early forms of memory loss and differentiate types of dementia. • Anxiety ○ Evaluate, screen, diagnose and potentially treat patients with anxiety. ○ Recognize the challenges one may encounter when caring for patients with anxiety. Additional details will be posted as soon as information is available.

Primary Care and Emergency Medicine is organized by Continuing Education, Inc. and will be held from Jan 09 - 16, 2021 at Royal Caribbean's Symphony of the Seas, Miami, Florida, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners, Pharmacists Accreditation: • 14 AMA PRA Category 1 Credits™ • 14 ACPE Credits • 14.0 Contact Hours Program Purpose: The purpose of this CME activity is to review and discuss common general medical conditions and to provide guidelines for their management and prevention. Topics have been chosen to benefit the family physician, general internist and Advance Practice Professionals in an ambulatory care setting Emergency Medicine encompasses a wide variety of topics that usually need emergent intervention. During this CME course, we will discuss topics that are important to the specialty that have recently undergone a change in management. We will also discuss common topics with unusual presentations or commonly missed diagnosis. The topics covered in this series are also great topics for all physicians or advanced practice providers, regardless of specialty as they are commonly seen in all patient populations and great knowledge for all. Topics: • Identifying and Managing Low Health Literacy ○ Understand which patient groups are at greatest risk for low health literacy ○ Appreciate the role that low health literacy plays on health outcomes ○ Review a simple intervention to identify the low health literacy patient • Preoperative Assessment of Cardiac Risk in Non-Cardiac Surgery ○ To appreciate causes of preroperative cardiac events ○ To understand which patients require preoperative assessment • Hypertension in African Americans ○ To understand the prevalence of hypertension in African Americans ○ To review social determinants of health which impact on effective treatment in this population • Rheumatoid Arthritis: A Primer for Primary Care Clinicians ○ Review the role of the primary care clinician in the co-management of rheumatoid arthritis ○ Describe the role of disease-modifying drugs (DMARDs) on the clinical course of rheumatoid arthritis • Physician Wellness and Resilience: Old Problem; New Urgency ○ To define physician wellness and the impact of physician stress on physicians and their patients ○ To describe new interventions to help physicians cope with wellness issues. • Heart Disease in Women ○ Appreciate sex-related differences in symptoms of ischemia between men and women ○ Review non-traditional risk factors for CAD impacting women that deserve special attention ○ Discuss strategies to raise awareness and close the gaps to optmize treatment of heart disease in men and women • Resistant Hypertension - Review of Case Studies to Enhance Understanding ○ Through the use of case studies review the epidemiology the clinical presentation and evidence-based approaches resistant hypertension (HTN) ○ Use current guidelines and algorithms to develop treatment plans for patients with HTN with an emphasis on resistant HTN • Pain Management without Opioids ○ Identify non-narcotic medications to use for pain management • Ride the C-O-O-l Wave: use of end-tidal CO2 in ED setting ○ Demonstrate the use of end-tidal CO2 in the ED setting • Pediatric Fever ○ Evaluate the use of ancillary tests in pediatric fever • Commonly missed x ray finding ○ Review common missed findings on x-rays • Bronchiolitis: what do I do? ○ Discuss current management in patients with Bronchiolitis • Laceration Tricks of the trade ○ Demonstrate the variety of laceration repairs available • I hit my head: when should I order a Head CT? ○ Examine the proper use of Head CT in head injury

PLEASE NOTE: THIS IS NOT A CURRENTLY ACTIVE PROGRAM. Cardiology, Lipidology, and Women's Health in the 21st Century: New Understandings and New Solutions is organized by Continuing Education, Inc. and will be held from Feb 28 - Mar 07, 2021 at Celebrity Edge, Fort Lauderdale, Florida, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners, Pharmacists. Accreditation: • 14 AMA PRA Category 1 Credits™ • 14 ACPE Credits • 14 (part II) MOC points in medical knowledge in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program • 14.0 Contact Hours • 7½ Hours of Pharmacology for NPs Description: Cardiovascular events remain the number one cause of death for women, yet little attention has been paid to the fact that women and men have great differences of their cardiovascular systems. Their different hormones also create differing impacts upon their immune, neurological, and musculoskeletal systems. The numerous ways estrogen affects the function of the female body has been overlooked by the conventional medical system, and in fact, was nearly buried by the infamous Women's Health Initiative (WHI) Study. The time has come to acknowledge the grave flaws of the WHI, and openly explore the myriad ways estrogen supports the female body and to acknowledge the grave impact of menopause on female cardiometabolic health. As well, the past 20 years has brought incredible new understandings of how the female body works, with revelations of the role of the gut microbiome, the circadian and lunar rhythms, the endocannabinoid system, and recognition of the healing effects of nutritional and lifestyle choices, as well as the benefits of fasting, all working synergistically to optimize female health. These lectures will explain every facet of these new understandings, ultimately presenting a therapeutic approach, each health care practitioner can implement in their practice, to optimize the health of every women patient, as she transitions into the menopause and during the remaining years of her life. Topics: • Estrogen & cardiometabolic health in women & the impact of menopause - part 1 ○ Define the metabolic impact of menopause due to loss of ovarian hormone production • Estrogen & cardiometabolic health in women & the impact of menopause - part 2 ○ Demonstrate knowledge of hormone therapy options in menopause, assessing prior studies and the newest data • Polycystic Ovary Syndrome: the poster child for female cardiometabolic dysfunction ○ Summarize the myriad reproductive and metabolic manifestations of PCOS and the underlying causes & new therapeutic approaches • Circadian rhythms, hormones, and cardiovascular health ○ Appraise the importance of rhythms to cardiovascular health and the role of clock genes and the master clock • The gut microbiome & cardiometabolic health - new dietary therapeutic approaches ○ Critique the gut microbiomer's role in maintaining cardiometabolic homeostasis & the impact of nutrition • Female-dominant medical conditions with cardiometabolic risk- but rarely recognized ○ Describe which chronic diseases often occurring in menopausal women are associated with serious cardiometabolic risk • Diagnosing & treating cardiometabolic issues in women - inflammation & fasting explored ○ Assess how inflammation underlies all cardiometabolic disease, how to diagnose it, and how to treat it with various forms of fasting • Update on Dyslipidemia ○ Apply knowledge gained to improve management of complex cholesterol related issues • Diabetes and CV disease: Focus on new treatments ○ Distinguish therapies in diabetes management that are beneficial or harmful from a cardiovascular perspective • Atrial Fibrillation: New therapies in stroke prevention ○ Gain insight into New Oral Anticoagulants and their judicious utilization • Hypertension: The debate about newer guidelines ○ Manage hypertension in a complex patient with multiple comorbidities • Congestive Heart Failure: evolving strategies in management ○ Synthesize diagnostics and create an algorithm based intervention using new therapies • Cardiorenal Intersection: The comorbidity conundrum ○ Classify types of CRS, employ biomarkers to predict AKI, CKD and ESRD and propose new hypothesis to generate ideas for new therapies • EKG Pearls: Clinical corelation ○ Analyze EKG abnormalities and corelate with potential clinical scenario Conference Sessions generally take place on days at sea (as itinerary allows), giving you plenty of time to enjoy your meals, evenings and ports of call with your companion, family and friends.

Endocrinology: An Update and Refresher for PCPs Co-Provided with School of Medicine, SUNY at Stony Brook is organized by Continuing Education, Inc. and will be held from Feb 21 - 28, 2021 at Royal Caribbean's Anthem of the Seas, Bayonne, New Jersey, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners Accreditation: • 14 AMA PRA Category 1 Credits™ • 14.0 Contact Hours Description: Objectives: This seminar will provide a working knowledge of common endocrinological problems. The course will reinforce physiology, pathophysiology, clinical manifestations, diagnosis and management of most major endocrine disorders. The current treatment for these disorders will be developed in sufficient detail to permit independent management or active participation in care with the endocrinologist. Emphasis will be placed on clinical diagnosis and practical treatment with attention to evidence-based medicine. Upon completion, participants should be able to recognize the signs and symptoms of most endocrinopathies; educate their patients regarding the basic concepts and natural history of these diseases and participate with their patients and consulting endocrinologists in decisions regarding modern disease therapy and prevention. This seminar will be relevant to family physicians, general internists, endocrinologists and others who manage patients with endocrinological disorders. Topics: • Diabetes mellitus in the 21st Century I: Diagnosis & management Guidelines • Diabetes Mellitus in the 21st Century II: Insulin Pumps and Glucose Monitors • Hypothyroidism • Hyperthyroidism • Dyslipidemia • Obesity and Insulin Resistance Syndromes • Osteoporosis • Hyperparathyroidism • Adrenal Mass • Thyroid Nodules • Thyroid Cancer Conference Sessions generally take place on days at sea (as itinerary allows), giving you plenty of time to enjoy your meals, evenings and ports of call with your companion, family and friends. Additional details will be posted as soon as information is available.

Sports Medicine Beating Anxiety and Depression: 2020 Update is organized by Continuing Education, Inc and will be held from Nov 29 - Dec 06, 2020 at Celebrity Edge, Fort Lauderdale, Florida, United States of America. Target Audience: Physicians, Physician Assistants, Nurses, Nurse Practitioners, Pharmacists, Psychologists, Social Workers Accreditation: • 14 AMA PRA Category 1 Credits™ • 14 ACPE Credits • 14 CE Credits for Psychologists • 14 ASWB ACE Credits • 14.0 Contact Hours • ½ Hours of Pharmacology for NPs Program Purpose: Topics: 1. Shoulder problems in the weekend athlete • To improve clinical diagnostic skills in the physical examination of the shoulder 2. Common knee problems are seen in primary care. • To improve clinical diagnostic skills in the physical examination of the knee 3. Concussion in sport: recognition and management for primary care providers. • To improve the level of comfort in the diagnosis and management of sports related concussions for primary care providers 4. Physical examination and joint injection techniques. • To improve skills in physical diagnosis and joint injection skills for primary care providers 5. Common foot and ankle problems in sports medicine. • To improve clinical diagnostic skills in the physical examination of the foot and ankle 6. Nutritional considerations for the young athlete- the female athlete triad. • To provide a rational approach to the diagnosis and management of the female athlete triad and nutritional issues 7. Exercise as medicine: The exercise prescription. • To help providers motivate their patients to do one of the best activities for their health:exercise! 8. Physicians in primary care need up-to-date, standardized and precise measuring tools for identifying SUD and their readiness for treatment • To assess levels of substance use in primary care. 9. In the last 20 years, physicians seek better strategies of managing Dual diagnosis (patients with mental health issues and SUD's) • How to manage a Dual Diagnosis. 10. Patient readiness for SUD treatment (or change) is often difficult to assess but is a very important variable in a successful outcome • Understand the conditions that facilitate change in addictive behavior? • Explain the stages of change model for primary care interventions. 11. Depression types and treatment • To use the most suitable cognitive-behavioral approaches to the treatment of depression. 12. Anxiety Types and treatmentatric disorders • To use most suitable cognitive-behavioral approaches to the treatment of anxiety.