Roni Shouval MD, PhD

Roni Shouval, MD, PhD, is Director of the Precision Cellular Therapy Laboratory and an attending on the Adult Bone Marrow Transplantation and Cellular Therapy Service at Memorial Sloan Kettering Cancer Center. His research focuses on deciphering mechanisms of resistance and toxicity in chimeric antigen receptor (CAR) T-cell therapy and hematopoietic cell transplantation (HCT). He integrates multiomic data—including genomic, transcriptomic, proteomic, radiomic, and microbiome profiles—with advanced computational approaches to uncover drivers of treatment failure and adverse events. Work from the Precision Cellular Therapy Laboratory informs clinical trial design and guides precision interventions aimed at improving the safety and efficacy of cellular therapies in hematologic malignancies.