The 10th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM)
In-Person Event
Sep 25 - 28, 2025
Berlin, Berlin, DE
15 CME 
OVERVIEW
The 10th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) is organized by CME Congresses Ltd and will be held from Sep 25 - 28, 2025 at Hotel nhow Berlin, Berlin, Germany.
Description:
COSTEM 2025 will serve as a dynamic platform for our community to engage, collaborate, and share the latest scientific research, clinical advancements, and ongoing developments in the field. The Congress fosters active participation through debate discussions, where global experts present and challenge positions on a wide range of pressing issues. This unique format offers clinicians an unparalleled opportunity to exchange insights, experiences, and innovative strategies to advance patient care.
This milestone event promises to be a progressive, thought-provoking, and informative experience. By addressing the most critical and controversial topics in the field, COSTEM 2025 aims to provide a fascinating forum that inspires dialogue, learning, and professional growth.
“Why should I attend?”:
COSTEM 2025 will showcase controversy debates within the following main topics – do not miss the chance to hear both sides of the debates and join the discussion where you and leading experts in the field will critically evaluate evidence, share experiences, and work towards consensus on pivotal issues.
Stay at the forefront of the field, sharpen your clinical decision-making, and contribute to shaping the future of patient care.
Main Topics:
- Acute leukemia
- Artificial Intelligence (AI)
- Bi-specific antibodies
- CMV infection
- CAR T-cell therapy and cellular therapy
- Cord blood transplantation
- Donor lymphocyte infusion
- Drug conjugated antibodies
- Genome editing and gene therapy
- GvHD prevention and treatment
- Haploidentical stem cell transplantation
- Hodgkin and Non-Hodgkin lymphoma
- Infectious complications
- Mesenchymal stem cell
- Multiple myeloma
- Myeloproliferative neoplasm
- Myelodysplastic syndrome
- NK Cell therapy
- Pediatric indications for transplantation
- Relapse prevention
- Stem cell transplantation
- TCR engendering based immunotherapy
- Toxicity post transplantation (VOD, TMA, etc.)
- Transplant for severe aplastic anemia and haemoglobinopathies
- Virus specific T Cell therapy
| Thursday, September 25 | |
|---|---|
| MTE Sessions | |
| 18:30 | Welcome Reception |
| Friday, September 26 | |
|---|---|
| 08:00-08:15 | Good Morning Coffee |
| 08:15-08:30 | Welcome Note Congress Co-Chairs |
| 08:30-10:00 | Session 1 |
| Controversy: Is PTCy or ATG-based prophylaxis the better haplo approach in AML? | |
| Moderator: Nicolaus Kröger, Germany | |
| 08:30-08:45 | ATG/ATLG: Xiaojun Huang, China |
| 08:45-09:00 | PTCy: |
| Controversy: Does HLA matter in HSCT with PTCy? | |
| Moderator: Arnon Nagler, Israel | |
| 09:00-09:15 | Yes: |
| 09:15-09:30 | No: Fabio Ciceri, Italy |
| 09:30-10:00 | Panel discussion: All session faculty |
| 10:00-10:20 | Coffee Break, Poster Viewing and Visit Exhibition |
| 10:20-11:50 | Industry-supported Symposium open timeslot |
| 11:50-12:00 | Technical Break |
| 12:00-13:30 | Session 2 |
| Controversy: Shall we include venetoclax in the induction chemotherapy and/or conditioning regimen before the transplant? | |
| Moderator: | |
| 12:00-12:15 | Yes: Thomas Schroeder, Germany |
| 12:15-12:30 | No: Jurjen Versluis, Netherlands |
| Controversy: Should we transplant TP53 multi-hit AML or MDS? | |
| Moderator: Mutlu Arat, Turkey | |
| 12:30-12:45 | Yes: |
| 12:45-13:00 | No: Avichai Shimoni, Israel |
| 13:00-13:30 | Panel discussion: All session faculty |
| 13:30-14:15 | Lunch Break, Poster Viewing and Visit Exhibition |
| 14:15-15:15 | Industry-supported Symposium open timeslot |
| 15:15-15:30 | Short Break |
| 15:30-17:00 | Session 3 |
| Controversy: Is there a future for CAR-T cell therapy in T-All? | |
| Moderator: | |
| 15:30-15:45 | Yes: He Huang, China |
| 15:45-16:00 | No: |
| Controversy: Are we ready for CAR-T in first-line therapy for MM? | |
| Moderator: Nico Gagelmann, Germany | |
| 16:00-16:15 | Yes: |
| 16:15-16:30 | No: |
| 16:30-17:00 | Panel discussion: All session faculty |
| 17:00-17:30 | Coffee Break, Poster Viewing and Visit Exhibition |
| 17:30-19:00 | Session 4 |
| Controversy: Does MRD before allo impact the outcome for MDS? | |
| Moderator: Ibrahim Yakoub-Agha, France | |
| 17:30-17:45 | Yes: Carmelo Gurnari, Italy |
| 17:45-18:00 | No: |
| Controversy: Is venetoclax the new partner for 5-Aza in MDS? | |
| Moderator: | |
| 18:00-18:15 | Yes: |
| 18:15-18:30 | No: Moshe Mittelman, Israel |
| 18:30-19:00 | Panel discussion: All session faculty |
| Saturday, September 27 | |
|---|---|
| 08:30-10:00 | Session 5 |
| Controversy: Is there a future for immunotherapy in AML outside allogeneic SCT? | |
| Moderator: | |
| 08:30-08:45 | Yes: |
| 08:45-09:00 | No: |
| Controversy: Is there a future for academic CARs? | |
| Moderator: | |
| 09:00-09:15 | Yes: Arnon Nagler, Israel |
| 09:15-09:30 | No: |
| 09:30-10:00 | Panel discussion: All session faculty |
| 10:00-10:20 | Coffee Break, Poster Viewing and Visit Exhibition |
| 10:20-11:50 | Industry-supported Symposium open timeslot |
| 11:50-12:00 | Short Break |
| 12:00-13:30 | Session 6 |
| Controversy: Splenectomy vs spleen irradiation in JAKi resistant MPN patients prior to alloSCT | |
| Moderator: Donal McLornan, UK | |
| 12:00-12:15 | Pro splenectomy: Nicola Polverelli, Italy |
| 12:15-12:30 | Pro spleen irradiation: Nico Gagelmann, Germany |
| Controversy: Does cord blood provide a stronger GVL effect than MUD? | |
| Moderator: Robert Soiffer, USA | |
| 12:30-12:45 | Yes: |
| 12:45-13:00 | No: |
| 13:00-13:30 | Panel discussion: All session faculty |
| 13:30-14:15 | Lunch Break, Poster Viewing and Visit Exhibition |
| 14:15-15:15 | Industry-supported Symposium open timeslot |
| 15:15-15:30 | Short Break |
| 15:30-17:00 | Session 7 |
| Controversy: Can modulation of microbiome by diet prevent or treat GvHD? | |
| Moderator: | |
| 15:30-15:45 | Yes: |
| 15:45-16:00 | No: |
| Controversy: Is fecal transplant the future treatment of SR-GvHD? | |
| Moderator: | |
| 16:00-16:15 | Yes: |
| 16:15-16:30 | No: |
| 16:30-17:00 | Panel discussion: All session faculty |
| 17:00-17:30 | Coffee Break, Poster Viewing and Visit Exhibition |
| 17:30-19:00 | Session 8 |
| Controversy: Is there a role for combining JAKi with other agents in acute and chronic GvHD? | |
| Moderator: Francesca Bonifazi, Italy | |
| 17:30-17:45 | Yes: |
| 17:45-18:00 | No: Olaf Penack, Germany |
| Controversy: Are MAGIC criteria and biomarker the standard for classifying and treating acute GvHD? | |
| Moderator: | |
| 18:00-18:15 | Yes: James Ferrara, USA |
| 18:15-18:30 | No: Amin Alousi, USA |
| 18:30-19:00 | Panel discussion: All session faculty |
| 19:00 | Poster Walk and Awards Session (Poster Area) |
| Sunday, September 28 | |
|---|---|
| 09:00-10:30 | Session 9 |
| Controversy: Can modern technology (e.g. AI) of large registries replace projective phase III studies? | |
| Moderator: Nicolaus Kröger, Germany | |
| 09:00-09:15 | Yes: |
| 09:15-09:30 | No: |
| Controversy: Can we expect CAR-T cells to treat GvHD? | |
| Moderator: | |
| 09:30-09:45 | Yes: |
| 09:45-10:00 | No: Bruce Blazar, USA |
| 10:00-10:30 | Panel discussion: All session faculty |
| 10:30-11:00 | Coffee Break |
| 11:00-12:30 | Session 10 |
| Controversy: CAR-T vs BITE in autoimmune disease | |
| Moderator: Raffaella Greco, Italy | |
| 11:00-11:15 | Pro CAR: |
| 11:15-11:30 | Pro BITE: Tobias Alexander, Germany |
| Controversy: CAR-T vs BITE in advanced follicular lymphoma | |
| Moderator: | |
| 11:30-11:45 | Pro CAR: |
| 11:45-12:00 | Pro BITE: |
| 12:00-12:30 | Panel discussion: All session faculty |
| 12:30 | Closing Remarks Congress Co-Chairs |
KEY DATES
25 Sep, 2025
Event Start Date
28 Sep, 2025
Event End Date
ACCREDITATION & CREDITS
EBAH CME Accreditation
The program of the 10th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) – September 25-28, 2025, Berlin, Germany has been reviewed and approved for CME accreditation by the European Board for Accreditation in Hematology (EBAH) CME Unit. The EBAH- CME Unit has approved this educational activity for a maximum number of CME credits. Each physician should only claim credits for time that she/he actually spent in the educational activity. We are pleased to inform you that the 2025 COSTEM Congress has been awarded:
- 15 EBAH-CME Credit Points
All participants may print a European Board for Accreditation in Hematology (EBAH) CME certificate indicating the number of EBAH-CME Credit Points awarded, directly from the system on the CME section of the EBAH website.
AEKB CME Accreditation
The 10th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) has been accredited by the Berlin Chamber of Physicians (Ärzetkammer Berlin) for a maximum of:
- 12 CME credits
Day 1 (September 26): 6 CME credits, Category B
Day 2 (September 27): 6 CME credits, Category B
Day 3 (September 28): 3 CME credits, Category B
Each medical specialist should claim only those days of credit that they actually spent in the educational activity. The Berlin Chamber of Physicians’ CMEC credit system is based on 1 CMEC per 45 minutes.
Please ask at the Registration Desk on-site to sign in each day in order to register your participation and receive your accreditation points.
TARGET AUDIENCE
PhysicianScientistsStudentsOncologistsResidentsNursesHematologistTraineesSPECIALITIES
HaematologyCell and Developmental BiologyHematology Blood and Marrow TransplantPediatric Hematology and Bone Marrow TransplantOncologyCONFERENCE SUMMARY
The 10th Congress on Controversies in Stem Cell Transplantation and Cellular Therapies (COSTEM) promises to be a pivotal event for professionals in the field. Scheduled for 2025, this conference will gather leading experts to discuss the latest advancements and challenges in stem cell transplantation. Attendees can expect in-depth sessions on innovative therapies, ethical considerations, and clinical outcomes. Networking opportunities will enhance collaboration among researchers and clinicians. This event is a must-attend for those looking to stay at the forefront of cellular therapy developments and improve patient care in transplantation.
SUGGESTED HOTELS
CONFERENCE VENUE
Hotel nhow BerlinCANCELLATION & REFUND POLICY
Cancellation Policy
All cancellations must be faxed, electronically mailed or postmarked. Refund of registration fees will be as follows:
- Postmarked up until July 31, 2025 – 100% refund (minus € 50 handling fee and bank charges)
- Postmarked from August 1, 2025 – 50% refund
- No refund on cancellations sent after September 11, 2025
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