The 2nd International 4 Corners of Cardiology 2014 was a great success and we are now delighted to announce dates for the 3rd meeting, to be held in Melbourne, 5th – 6th February, 2016. As with the first two meetings, the focus of 4C Cardiology 2016 will be on high-level updates, debates, hot topics and future research directions in 4 key areas of cardiovascular medicine. This format has proven to be extremely popular with both clinicians and researchers, and the scientific content formally endorsed by the European Society of Cardiology. Check the website for updates and join us in Melbourne for what promises to be another exciting, cutting edge exploration of the latest advances in cardiovascular medicine.