Richard Daneman BSc, PhD

Richard Daneman received his Bachelor of Science McGill University, in Montreal Canada majoring in biochemistry. Daneman then received his Ph.D in developmental biology from Stanford University where he studied the molecular mechanisms that regulate blood-brain barrier (BBB) formation in the laboratory of Dr. Ben Barres. Daneman then started his own lab as a Sandler Fellow at University of California, San Francisco, before moving to a position as Assistant Professor in the departments of Pharmacology and Neuroscience at the University of California, San Diego.

Daneman focuses his studies on understanding the molecular mechanisms that regulate BBB function during health and disease. In his lab, he uses a combination of cellular, molecular and genetic approaches to understand the mechanisms of BBB formation and function, addressing important questions such as: What are the molecules in CNS vascular cells that form the BBB? What are the signaling mechanisms that regulate the formation of the BBB during development, and dynamic function throughout life?. What are the molecular mechanisms that lead to BBB disruption during neurological disease? The overall goal of his work is to elucidate these mechanisms, such that we will be able to develop therapeutics to rebuild the barrier to treat neurological diseases, as well as methods to bypass the barrier to deliver drugs to the CNS.