Atypical hemolytic uremic syndrome (aHUS): therapeutic updates and optimizing treatment

Atypical hemolytic uremic syndrome (aHUS): therapeutic updates and optimizing treatment is organized by ScientiaCME. 

Release Date: July 10, 2019
Expiration Date: July 10, 2021

Accreditation:
Credit Designation: ScientiaCME designates this educational activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)™ toward the AMA Physician's Recognition Award. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Pharmacists:
ScientiaCME is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmaceutical education. This program is approved for 1.00 hours (0.10 CEUs) of continuing education. Proof of participation will be posted to your NABP CPE profile within 4 to 6 weeks to participants who have successfully completed the post-test. Participants must participate in the entire presentation and complete the course evaluation to receive continuing pharmacy education credit. ACPE # 0574-0000-19-021-H01-P. ACPE Accreditation effective 7/14/19 and expires 7/14/21. 

Description:
In this online CME self-learning program:
Atypical hemolytic uremic syndrome (aHUS) is a disease in which the complement system is activated in an uncontrolled manner outside the presence of coexisting disease, resulting in platelet activation, damage to endothelial cells, and a range of clinical sequelae including: which may ultimately lead to kidney failure; systemic thrombotic microangiopathy;anemia; and thrombocytopenia.The disease may arise from any of a number of genetic mutations of the complement system or the presence of anti-complement factor H. While it is estimated to occur at an equally commonly between males and females, the disease is rare with an estimated incidence of about 2 people per million in the U.S. and seven per million in Europe.

Objectives:
By the end of the session the participant will be able to:
• Describe the pathophysiology of aHUS such that it might informs pairing with present treatment mechanisms
• Describe aHUS diagnostic methods, differential diagnosis, and the benefits of earlier diagnosis
• Describe available therapies used for treatment of aHUS and summarize the literature supporting use of those therapies
• Design an evidence-based treatment plan for a patient with aHUS