21st-Century Drug Discovery and Development for Global Health (S3) is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from Oct 17 - 20, 2018 at Hotel Palace Berlin, Berlin, Germany.
Overview:
Infectious diseases cause substantial morbidity and mortality in the developing world. The medicines available today are often inconvenient to use or result in side effects, and many are being lost to emerging drug resistance. There remains an urgent need to discover and develop the next generation of transformative medicines that are more efficacious, more highly targeted, and have a better safety profile. This will only be achieved through the application of state-of-the-art drug discovery tools, technologies, and approaches. This conference will focus on diseases caused by parasitic organisms and bacteria, including malaria, neglected tropical diseases, diarrheal disease, and tuberculosis. The goals of the conference are to improve understanding of the disease burden and challenges faced in developing new therapies, to highlight examples of progress towards new drug candidates, and to foster communication and collaboration among communities of researchers working in global health across the spectrum from research to the clinic. The symposium will be of interest to basic scientists as well as drug discovery and development experts seeking to gain a better understanding of the challenges and opportunities in global health.
Plenary Session Topics:
• New Therapeutics for Global Health
• Robust Target Validation – What Does it Mean?
• Importance of Chemical Diversity in Seeking New Leads
• Workshop 1: Novel Clinical Trial Design
• Alternative Approaches to Drug Delivery - Opportunities and Challenges
• Improving Target and Phenotypic-Based Approaches
• Workshop 2: Opportunities for Repurposing to Discover New