The mission of Advances in Neurological Therapeutics 2013 is to update regional practitioners on the therapeutic effects of current and emerging therapies for Parkinson’s disease (PD), multiple sclerosis (MS), Alzheimer’s disease (AD) and other dementias. The importance of early diagnosis for these diseases will be stressed, and the risks and benefits of current and emerging therapies will be covered. We will also discuss the use of physical therapy and biomedical devices as a means to manage these diseases and improve patient function and quality of life. Finally we will explore the psychiatric issues faced by individuals with neurological disease, as well as discuss the bioethical implications of PET imaging of the brain. We intend to provide an engaging forum, which will motivate practitioners to think holistically when treating patients with PD, MS, and AD.