Ueli Schibler PhD

Ueli Schibleris an expert in the field of gene expression during the circadian cycle. Since 1984, he is Professor of Microbiology at the University of Geneva. On 14 September, he will receive the Aschoff-Honma Prize, awarded every two years and rewarding exceptional achievement of progress in the field of research on biological rhythms. This award is in addition to numerous awards received during his career.

The current theme of his research, says Ueli Schibler duty to serendipity: "Early in my career, I was particularly interested to understand how it is possible that the same genes are present in all tissues, are expressed more or less strongly in different tissues. Genes expressed in the liver are, for example, very different from those expressed in the kidney, although the genetic information contained in each cell is the same. The specific activity of the genes depending on the fabric is controlled by regulatory proteins called transcription factors. In the mid 80s, we were able to develop a biochemical system in vitro that helped us identify some of these factors. "