Steven Louis ShaferMD
Steven L. Shafer has a work in pharmacology includes studies of many of the intravenous opioids and hypnotics used in anesthetic practice. My focus has been mathematical models that characterize drug behavior. These range from conventional pharmacokinetic and pharmacodynamic models, inverse models (used to drive target controlled infusion systems), Bayesian models (used to handle model uncertainty), models of drug interaction, and models of receptor function that help elucidate mechanisms of drug action. My most recent work has explored whether neural networks offer any benefits over the standard engineering models used in pharmacokinetics and pharmacodynamics.
My work in publication policy and ethics follows my 10 years as Editor-in-Chief of Anesthesia & Analgesia. From 2006-2016 we uncovered two of the most prolific serial academic fraudsters in history. I finished my term as EIC with the unenviable record of retracting more papers than any previous journal editor. Fortunately, this led to a lasting interest in publication policy and ethics. In collaboration with others I continue to develop statistical models to detect fraud, and serve on multiple editorial boards to offer guidance on publication policy and ethics.