Stephen West PhD

Stephen West was born in Hessle, Yorkshire, in 1952. He studied biochemistry at Newcastle University before moving to the USA to carry out post-doctoral work with Paul Howard-Flanders in the Department of Molecular Biophysics and Biochemistry at Yale University. In 1985, he moved back to the UK to set up a research group at the Imperial Cancer Research Fund's Clare Hall Laboratories at South Mimms (which became the Cancer Research UK London Research Institute in 2002 and the Francis Crick Institute in 2015). He is now a Senior Group Leader at the Crick.

Stephen West has been a leader in the fields of genetic recombination and DNA repair for the past three decades. As his work crosses the boundaries between basic research studies of DNA repair and tumourigenesis, and he is a frequent keynote speaker at major international meetings. Steve plays an active role in the organisation of international conferences, and currently organizes the biannual ‘Recombination Mechanisms’ conference. He also organised the first Annual EMBO Conference (with Hans Clevers) in 2009, and is coorganiser of a number of DNA repair conferences in Europe and Asia. Steve's research centres on mechanisms of genetic recombination and DNA strand break repair. In particular, he has defined relationships between defective DNA repair processes and human diseases such as inheritable breast cancer and neurological disorders.