Nieves Gonzalez GomezPhD
Dr. Gonzalez has more than 17 years’ experience in metabolic disorders as diabetes and obesity. She has conducted a scientific work mainly related to both diseases, inhuman and animal models. Specifically, she has performed significantly and relevant studies focus on the effects and mechanisms of action of anti-diabetic compounds (v.g.: GLP-1, exendins, amylin) in extrapancreatic tissues. Moreover, she developed pharmacological studies of bombesin receptor family –GRPR, NMBR y BRS-3– which are involved in multiples pathologies (prostatic, breast, pancreatic, colorectal, gastric and esophageal cancers). Recently, she has carried out in vitro assays in human muscle and adipose cells, which propose BRS-3 as a potential molecular target for diabetes and obesity. Beyond that, her future projects include the study of the influence of impaired glucose homeostasis in neuronal function. The treatment of peripheral and central pathology of Huntington disease could form the basis for a more effective therapeutic strategy, since the maintenance of a healthy nervous system, is closely linked to metabolic health.