Frederick A. Schmitt PhD

Dr. Frederick A. Schmitt, PhD is a Professor of Neurology with joint appointments in the Departments of Psychiatry, Psychology, Neurosurgery, and Behavioral Science. He also holds an appointment as a Center Associate in the Sanders-Brown Center on Aging and Spinal Cord and Brain Injury programs at the University of Kentucky (UK).

He is a clinical scientist with a primary focus on the evaluation of the relationship between physiological changes associated with normal aging, Down syndrome, and dementia associated with neurodegenerative diseases. Dr. Schmitt has been an investigator on multiple multidisciplinary program project grants, the Alzheimer’s Disease Center at UK where he works in the Clinical and Biostatistics Cores. He has coordinated multiple studies of experimental therapies for MCI and AD.

His present research, along with his colleagues, involves an antioxidant AD prevention trial (with over 7,500 participants), statistical models of mixed dementia neuropathology, as well as diffusion tensor imaging and plasma proteomics as predictors of dementia evolution in Down syndrome.