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Home  >  Speakers  >  Elaine S. Jaffe
Elaine S. Jaffe

Elaine S. Jaffe

    MD, FASCP
Senior Investigator | Bethesda, Maryland    United States Of America
Pathology, Hematology Blood And Marrow Transplant,...More
Pathology, Lymphoma,...More
Spoken at 3 events

Biography :

Dr. laine Jaffe, MD, FASCP, is the senior investigator in the pathology laboratory and head of the Hematopathology Section in the Center for Cancer Research at the National Cancer Institute. She has conducted pioneering studies related to the classification of malignant lymphomas and has led an international effort for consensus among clinicians and pathologists. Her work focuses on lymphomas as tumors of the immune system.

Using a combination of immunophenotypic, genomic and genetic approaches, her research team is examining the pathogenesis of lymphomas, mechanisms of transformation, and signaling pathways involved in control of cellular proliferation and differentiation. These studies delineate new disease entities and provide a basis for therapy. Her work has established a new paradigm for the classification of lymphoid neoplasms.

Her areas of expertise include Lymphoma Diagnosis, Immunophenotypic Studies, Non-Hodgkin’s Lymphoma, Hodgkin’s Lymphoma, Epstein Barr Virus, and Lymphoproliferative disease. Disease discovery and disease definition are critical first steps in elucidating pathogenetic mechanisms of cancer. Most insights into the molecular pathogenesis of lymphomas have followed on the heels of a precise elucidation of the disease entity based on clinical, pathological, or immunophenotypic grounds.

Dr. Jaffe’s research team focuses on the definition of malignant lymphomas as tumors of the immune system, delineation of new disease entities, studies related to the pathophysiology of malignant lymphomas, and clinical correlations including prognosis and response to treatment. These studies were instrumental in the development of the WHO Classification of Tumours of the Hematopoietic and Lymphoid Tissues, published by the International Agency for Research on Cancer in 2001 and revised in 2008.

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Specialties

Pathology, Hematology Blood and Marrow Transplant, Research/Clinical Research

Interested Topics

Pathology, Lymphoma, Immunophenotypic Studies, Lymphoproliferative disease, Non-Hodgkins lymphoma, Hodgkins lymphoma, Epstein Barr virus, Cell Proliferation, lymphoproliferative disease, Signaling pathways

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Languages

English

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