Charles Louis Edelstein MD, PhD

Dr. Charles Edelstein is a Professor of Medicine at the University of Colorado Denver. Through his Department of Veterans Affairs Merit Award, Dr. Edelstein investigated the pathophysiology of cisplatin-induced acute kidney injury (AKI) in a clinically relevant model of mice with cancer. In his renewed VA Merit award, he will study the role of autophagy in polycystic kidney disease. Through his industry and Department of Defense-funded grants, Dr. Edelstein investigates the mammalian target of rapamycin signaling and autophagy in rodent models of polycystic kidney disease (PKD). He is the principal investigator on numerous clinical studies in patients with PKD and is interested in biomarkers of AKI, having edited a book on biomarkers in kidney diseases. Dr. Edelstein does inpatient attending at both the VA and University Hospitals and has a weekly clinic at the University Hospital that specializes in PKD.