Andrew Michael Davidoff MD

Andrew Davidoff, MD, maintains an active NIH-funded research lab that focuses on angiogenesis and gene therapy, both for cancer therapy and the treatment of monogenetic disorders. Inhibiting the new blood vessel formation (angiogenesis) required for tumor growth has proven to be an effective alternative anti-cancer strategy. However, anti-angiogenic therapies are likely to prevent tumor growth rather than actually kill the tumor cells, and so once the restrictions of angiogenesis inhibition are ended, tumor regrowth may recur. Therefore, Dr. Davidoff is studying the potential of chronic delivery of these agents by gene therapy techniques to maintain anti-tumor activity.