Andres Hidalgo is Currently working as an Assistant Professor at National Center for Cardiovascular Research in Madrid, Spain. He is interested in the cellular and molecular mechanisms by which innate immune cells, and their hematopoietic precursors, contribute to organismal physiology and pathology. As a postdoctoral trainee, he developed and used live imaging modalities to study acute inflammatory disease and discovered the receptors that mediate early neutrophil recruitment, and the signals that cause acute vascular injury. As an independent researcher at CNIC (Spain), His laboratory further developed tools to study thrombo-inflammation and the dramatic consequences in several organs, including the lung, brain, and heart. He discovered new functions for innate immune cells and demonstrated that circadian rhythms in the bone marrow are entrained in part by neutrophils entering this organ and that these rhythms are critical for immune defense and inflammation. He is also interested in other types of innate immune cells, such as resident macrophages of the heart. As a professor at Yale, he is interested in defining the fundamental organization and function of innate immune cells, from their development and specification under homeostasis, to their reparative or disease-promoting roles.
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