Should Antimicrobial Doses be Fixed? Weight Weight...Don’t Tell Me! (ACPE Credit)

Should Antimicrobial Doses be Fixed? Weight Weight...Don’t Tell Me! (ACPE Credit) is organized by Society of Infectious Diseases Pharmacists (SIDP).

Release Date: 09-26-2019
Expiration Date: 09-26-2022

Course Description:
One out of three adults in the United States are obese but the most optimal approach to antibiotic dosing in this population remains controversial. For antibiotics that are weight-based, selection of the best body size descriptor is often unclear when managing a patient that is obese. Likewise, concerns exist about whether a “one-size-fits-all” dosing regimen is sufficient for a patient that is obese. This webinar will provide a historical and contemporary perspective on the definition of obesity and body size description. The pharmacologic approach to initial and maintenance dose selection will be reviewed to harmonize current divergent approaches. Patient case and drug case scenarios will illustrate pragmatic methods of informing antibiotic dose selection in obesity.

Learning Objectives:
The target audience for this activity includes pharmacists. At the completion of this activity, the participant will be able to:
• Review the epidemiology and definition of obesity.
• Outline the rationale for optimal dose selection.
• Link pharmacokinetic parameters with the choice of initial and maintenance dose selection.
• Illustrate the similarity and differences in body size scalars for drug dosing across ages.
• Discuss the rationale for alternate approaches to dose selection.
• Review specific antimicrobial dosing approaches to demonstrate potential areas of improvement.