OVERVIEW

Community Practice Connections™: Precision Medicine in Oncology: Current Role and Future Potential of In-House Next-generation sequencing (NGS) Technologies is organized by Physicians' Education Resource, LLC (PER).

Release Date: January 6, 2020
Expiration Date: January 6, 2021

Accreditation:
Physicians’ Education Resource®, LLC, designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Activity Overview:
Next-generation sequencing (NGS) is a widely used instrument in the field of adult hematology/oncology. However, key differences between pediatric and adult cancers at the genetic level limit the utility of the most well-established NGS panels for pediatric cancer testing. With the emergence of pediatric-tumor–specific testing assays, it is important for clinicians to remain up to date on the latest technologies to ensure that their patients with childhood cancers receive the best possible care. This activity will provide you with an overview of the history of NGS in cancer care and its developing role in pediatric hematology/oncology; the rationales for the different testing platforms, along with their utility, strengths, and limitations; and a critical evaluation of data supporting clinical application of established biomarkers in a variety of pediatric cancers.

Learning Objectives:
Upon successful completion of this educational activity, you should be better prepared to:
• Outline the clinical implications of next-generation sequencing (NGS) for pediatric and young adult patients with cancer.
• Develop evidence-based strategies to individualize treatment of pediatric and young adult patients with cancer based on assessment of tumor profile and patient characteristics.
• Identify the role of multidisciplinary teams to facilitate, interpret, and implement novel in-house NGS technologies in clinical practice.
• Assess methods to overcome barriers to facilitate the use of NGS strategies for pediatric and young adult patients in community settings.

Benefits of Participating:
• Learn the latest information regarding the optimal use of NGS in pediatric cancer, including the specific ways it can contribute to diagnosis and treatment
• Compare and contrast current and emerging NGS technologies
Learn from case studies how the use of NGS can be applied in a variety of different malignancies
• Hear expert perspectives on where this field is headed and how it may benefit patients now and in the future