OVERVIEW

Fatal Factors of Sickle Cell Trait is organized by National Society for Histotechnology (NSH) and will be held on Oct 22, 2025.

Description:
Sickle Cell Trait (SCT) affects nearly 300 million people worldwide. Awareness that SCT is not an entirely benign condition is growing, but many pathologists and clinicians overlook the fact that sickling may become fatal under certain conditions in patients with the trait. At autopsy, micro-occlusive sickling is identified and SCT is confirmed by postmortem hemoglobin fractionation which proves the trait to be a contributory factor to the cause of death. This workshop discusses the controversy of SCT as a contributory cause of death, and explores autopsy findings in hospitalized patients with SCT dying of natural disease. Participants will get an understanding of the difference between the trait and the actual disease. We will also take a glimpse at S/E hemoglobinopathy, a rare form of sickle disease.