8th Annual PREDiCT: Tumour Models Summit

8th Annual PREDiCT: Tumour Models Summit is organized by Hanson Wade and will be held from Dec 04 - 06, 2019 at DoubleTree by Hilton Hotel London - Tower of London, London, England, United Kingdom.

How Can Your Preclinical Oncology Models Influence and Translate into Clinical Success?

The 8th annual PREDiCT: Tumour Models London will return this December with a fresh speaker faculty to help you benchmark your oncology model selection strategy and target validation. With the rise of immuno-oncology, model requirements, target validation and the importance of tumour micro-environment are key to clinical success. The 3-days summit will provide you with real world data from a selected model experts, including Merck Healthcare KGaA, MedImmune, Kymab, Leiden University, Basilea Pharmaceutica for practical insights.

Unmissable Case Studies:
• Unique PDX models to advance liquid-biopsy research and immunotherapy (Rabin Medical Center)
• Assessment of different humanised mouse models for the evaluation of cancer immunotherapies (Sanofi)
• Innovative models with increased clinical relevance and predictive value for in vivo profiling of cancer immunotherapies (Roche Innovation Center)
• Complementary models to study oncolytic virus immunotherapy (National Center for Tumor Diseases)
• Improving translational gap of preclinical outcomes through PKPD modelling (AstraZeneca)

Join this community to meet 100 like-minded translational, in vivo and pharmacology scientists to discuss how to enhance predictiveness and translatability of your preclinical models.

Workshop A
Utilising Bioinformatics to Advance Preclinical Decision Making
9:00 am to 12:00 pm
Attend this workshop to learn:
• How to define the quantitative relationship between preclinical efficacy and clinical activity for I/O therapeutics
• Discuss the possibility to set minimum preclinical efficacy criteria to qualify a novel treatment for clinical success
• Apply translational modelling framework insights to best support drug projects

Workshop B
Validation Techniques Using Humanised Mouse Models
1.00pm - 4.00pm
This workshop will explore the different strategies of immune system humanisation in mice as well as to review challenges, insights and future directions for mouse and humanised models within oncology.

Attend this workshop to learn:
• What is the state of the art of humanised mouse models?
• What is the pre-requisite that a humanised mouse model is a good model for studying cancer?
• Do current humanised mouse models satisfy the need for cancer research?

Time: 9:00 am - 5:00 pm