Upcoming Medical Conferences in Keystone

Tumor Metabolism (B5) is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from Feb 24 - 28, 2019 at Keystone Resort, Keystone, Colorado, United States of America. Course Description : Research over the past decade has considerably enhanced our understanding of metabolic changes that occur as cancers emerge from normal tissues, and it has become apparent that tumors evolve numerous mechanisms to obtain the nutrients they need to grow and to cope with the reactive oxygen species that are generated during high rates of growth. This Keystone Symposia conference will focus on approaches to identify and therapeutically exploit the various metabolic vulnerabilities of tumor cells compared to normal tissues. The major goal is to discuss how to develop new therapies to kill tumors based on emerging knowledge about metabolic vulnerabilities. As new drugs that target metabolism enter the clinic, we need biomarkers that reveal which tumors are likely to be vulnerable and biomarkers that reveal mechanisms of resistance. Specific aims are to: •  Understand how and why different tumor types evolve different mechanisms to obtain nutrients •  Explore how tumor cells protect themselves from reactive oxygen species •  Investigate differences in metabolism of metastatic tumors compared to primary tumors •  Understand how whole body metabolism relates to tumor metabolism, and •  Enhance our ability to monitor tumor metabolism via minimally invasive imaging. The anticipated outcomes are the sharing of unpublished discoveries about mechanisms used by primary and metastatic tumors to obtain nutrients from their environment as emerging technologies for monitoring tumor metabolism in vivo and ex vivo. The conference will bring together scientists and clinicians with widely different backgrounds in preclinical models of cancer, drug discovery, drug development, imaging and clinical trials to share information about: •  The diverse ways that tumors alter metabolism •  New drug targets suggested from this knowledge of tumor metabolism •  New technologies to monitor tumor metabolism in vivo and ex vivo •  Progress being made in pre-clinical studies with experimental approaches that alter tumor metabolism, and •  Progress in human clinical trials with new drugs that target metabolism. Plenary Session Topics: • Cancer Cell Metabolism • Feeding the Cancer • Metabolism and Metastasis • The Metabolism of ROS and Survival • Metabolism Outside the Tumor • Metabolic Adaptation and the Response to Therapy • Imaging Cancer Metabolism in vitro and in vivo • Modeling Cancer Metabolism in vitro​ Additional details will be posted as soon as they are available.

Innate and Non-Classical Immune Cells in Cancer Immunotherapy (C5) is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from Mar 24 - 28, 2019 at Keystone Resort, Keystone, Colorado, United States of America. Course Description : Immunotherapy has revolutionized the treatment of many cancer types over the past five years. T cell checkpoint inhibitors have led the way and are the focus of most immunotherapy trials. However innate and non-classical T cells contribute extensively to the tumor infiltrate and significantly impact on the tumor immune response in both the tumor microenvironment and in circulation. This symposium aims to bring together academic and industry opinion leaders in the fields of innate immune cells, natural killer cells, tumor microenvironment, tumor immune suppression, novel immunotherapeutic strategies and clinical cancer immunotherapy to define the next wave of immunotherapy breakthroughs that reach beyond the current T cell checkpoints. The meeting offers a unique opportunity for an audience of diverse immunology and cancer research backgrounds to come together and share cutting edge insight into cancer immunology and rationale approaches for therapeutic intervention that could be used as be stand alone or in combination with T cell checkpoint therapies. A key aim is to bring together experts with complementary interest in cancer immunotherapy that would not normally be drawn to common symposia and foster new dynamic collaborations to advance our understanding of tumor immunity. Additional details will be posted as soon as they are available.

Neural Environment in Disease: Glial Responses and Neuroinflammation (Z1) is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from Jun 16 - 20, 2019 at Keystone Resort, Keystone, Colorado, United States of America. Course Description : The response of the central nervous system to injury and disease is a complex physiological process that involves the coordinated actions of many different cell types. The interplay of neural cells and vascular cells along with the innate and adaptive immune systems determines the response to different injury and disease stimuli and whether there nervous system will repair or degenerate. Understanding these complex cellular environment is essential to understanding disease pathogenesis, elucidating underlying disease etiology, and developing treatments for neurological and psychiatric diseases. The goal of this meeting will be to bring together people who study different aspects of neurological diseases and facilitate the interchange of ideas necessary for identifying new mechanisms underlying complex intercellular interactions in the diseased nervous system. This will include people who study resident neural cells (neurons, astrocytes, oligodendrocytes), vascular cells (blood-brain barrier, lymphatics, glymphatics) and immune cells (microglia, innate peripheral immune cells, adaptive immune cells) in the context of a variety of neurodegenerative, neuroinflammatory, and neuropsychiatric diseases. Further, we will also attract people who implement different techniques including genetic mouse models, human iPSCs, invertebrate models, imaging, cell biology, and behavior in their research which will further facilitate exchange of ideas and foster collaboration. With the combined expertise at this meeting, we will accelerate our ability to understand the complex neural response to injury and disease-a necessary step towards developing novel therapeutics for complex neurological diseases. Additional details will be posted as soon as they are available.

Neurodegenerative Diseases: New Insights and Therapeutic Opportunities (Z2) is organized by Keystone Symposia on Molecular and Cellular Biology and will be held from Jun 16 - 20, 2019 at Keystone Resort, Keystone, Colorado, United States of America. Course Description : The global burden of neurodegenerative disease is staggering and growing at an alarming rate as the worlds populations age. While Alzheimer’s disease and related dementias and Parkinson’s disease and related disorders account for the majority of those afflicted, there are also less common but equally devastating diseases. Technical and conceptual advances are revealing disease mechanisms and providing new therapeutic opportunities. Misfolded proteins have been understood to be at the center of neurodegenerative diseases but recently there is an appreciation that these misfolded proteins may serve as seeds to template the misfolding of normal proteins, that transmission of these seeds may under lie disease progression, and there may be different strains of these seeds with differential toxicities. Biophysical analysis of these proteins reveals a role for phase transition and liquid demixing of these intrinsically disordered proteins. Synaptic loss is an important feature of neurodegeneration which may occur long before neuronal loss, but be critically important in disease presentation and loss of function. Glia and immune activation contribute to neurodegeneration and synaptic loss, and must be understood and controlled if the disease process is to be tempered or stopped. This conference aims to address the current state of knowledge in these emerging areas, to provide advanced discussion of these topics, to provide the opportunity for interaction between scientists from different fields of research and foster new collaborations that may lead to new therapeutic opportunities to combat the coming crisis in providing medical care for those suffering from neurodegenerative diseases. Additional details will be posted as soon as they are available.

2019 National Nurse Practitioner Symposium is organized by National Nurse Practitioner Symposium and will be held during Jul 18 - 21, 2019 at Keystone, Colorado, United States of America. The target audience for this medical event is nurses. Additional details will be posted as soon as they are available.

2020 National Nurse Practitioner Symposium is organized by National Nurse Practitioner Symposium and will be held during Jul 09 - 12, 2020 at Keystone, Colorado, United States of America. The target audience for this medical event is nurses. Additional details will be posted as soon as they are available.

2021 National Nurse Practitioner Symposium is organized by National Nurse Practitioner Symposium and will be held during Jul 08 - 11, 2021 at Keystone, Colorado, United States of America. The target audience for this medical event is nurses. Additional details will be posted as soon as they are available.

AEI - The 2018-19 Medical-Dental-Legal Update is organized by American Educational Institute (AEI) and will be held weekly from Dec 03, 2018 - Apr 12, 2019 at Lenawee Condominiums, Keystone, Colorado, United States of America. The target audience for this medical event is Physicians, Dentist and other Healthcare Professionals. This CME Conference has been approved for a maximum of 20 AMA PRA Category 1 Credits, 20 ABIM MOC, 16.75 AAFP Credits, 20 AOA Category 2-B Credits. Conference Description: You practice in a dynamic and challenging environment. While keeping clinically current is imperative, it isn't enough. You must also acquire the skills necessary to navigate a professional liability minefield, manage a more effective and efficient practice, and navigate a maze of healthcare laws and regulations. The 2018–19 Medical-Dental-Legal Update Update is designed to assist you in that endeavor. The course, offered weekly in 32 enviable destinations, is a unique, 20-hour survey of the intersection of medicine and law as well as selected clinical topics. Produced in state-of-the-art production studios with broadcast-grade, HD digital technology. Conference Objectives are: • Understand and avoid malpractice litigation. • Identify and reduce healthcare office risk. • Understand and start a direct patient care practice. • Protect professional and personal assets. • Utilize non-pharmacologic techniques for managing chronic stress. • Utilize a variety of clinically relevant but relatively unknown treatments. • Consult patients on the benefits of a longevity diet. • Utilize aspirin as a primary prevention agent for CVD, stroke and colon cancer. • Understand risks and benefits of cannabis and cannabinoids in pain management. • Understand and utilize common imaging modalities and techniques. • Identify and avoid legal and ethical pitfalls of treating unreasonable patients. • Implement new type 2 diabetes practice guidelines aimed at cardiovascular risk reduction. • Interpret chest X-rays for common clinical conditions. • Improve practice profitability through more efficient patient flow. • Reduce professional financial stress by better benefit planning. • Understand and reduce medication nonadherence. • Understand Alzheimer’s di­sease and better interact with afflicted patients. • Understand and manage malpractice litigation stress. • Incorporate the relationship between diabetes and oral health into patient care. Meetings Dates: Every Week, Monday - Friday 7:30 - 9:30 am. & 4:00 - 6:00 pm Additional details will be posted as soon as they are available.