Zongbing You MD, PhD

Dr. You received his M.D. from the West China University of Medical Sciences in 1989. He conducted his doctoral studies on the chemotherapy of gynecologic cancer under the tutelage of Dr. Zeyi Cao at the same institution, obtaining his Ph.D. in 1994. From 1994 to 1998, Dr. You was a postdoctoral fellow and then a faculty member at the Beijing Medical University, working on the molecular biology of gynecologic cancer. In 1998, Dr. You joined the University of Freiburg, Freiburg, Germany, as a research scientist to investigate adenovirus-mediated cancer gene therapy. In 2000, he moved to the University of Michigan, Ann Arbor, as a research fellow focusing on molecular signaling and apoptosis in cancer. In 2003, Dr. You joined the faculty of the University of California Davis as an adjunct instructor and then an adjunct assistant professor in the Department of Orthopaedic Surgery, working on the interleukin-17 receptor-like molecule (IL-17RL or IL-17RC) in prostate cancer. In 2008, Dr. You joined the faculty of the Tulane University Health Sciences Center as an assistant professor in the Department of Structural and Cellular Biology. In 2014, Dr. You was promoted to associate professor with tenure. Dr. You's cancer research interest is to understand the role of inflammation in cancer initiation, promotion, and progression. His target molecule in inflammation is interleukin-17 (IL-17). IL-17 is a key cytokine in many inflammatory and autoimmune diseases. His lab is using in-vitro and in-vivo (transgenic and knockout mice) approaches to determine the role of IL-17 signaling in the initiation, promotion, and progression of prostate cancer. The long-term goals of these studies are to identify the molecular mechanisms of IL-17 signaling pathways, to develop new methods targeting IL-17 signaling, and to apply these methods in the prevention and treatment of prostate cancer.