Young-bum KimBS, MS, PhD
Dr Kim is currently an Associate Professor of Medicine at Harvard Medical School and Beth Israel Deaconess Medical Center. His training included two master’s degree, one from the Kon-Kun University in Korea and the other from University of Tsukuba in Tsukuba, Japan where he also received his PhD in Molecular Physiology. Dr Kim is interested in human metabolism because of the crucial roles that glucose and energy homeostasis play in health and disease. His research focuses on identifying the molecular mechanisms mediating the metabolic action of insulin and leptin, and the resistance to these hormones that underlies diseases such as obesity and diabetes.
To identify the metabolic roles of specific molecular signals, his lab uses genetically engineered mouse models and cultured cell systems, in conjunction with biochemical, molecular, and physiological techniques. Using these techniques, he found that Rho-kinase regulates insulin-stimulated glucose transport and signaling via either IRS-1 serine phosphorylation or actin polymerization, and also controls energy balance by targeting leptin receptor signaling, establishing a new mechanism for the regulation of insulin and leptin action. He is also an editorial board member for Diabetes, Journal of Biological Chemistry, Molecular Metabolism, the American Journal of Physiology and Endocrinology, an associate editor of Metabolism and serves on the research grant review panel of the NIH, American Diabetes Association, Endocrine Society and several international funding agencies.