Yotis SenisMSc, PhD
Dr. Yotis Senis was awarded a BSc in Life Sciences in 1993, an MSc in 1996 and a Ph.D. in 2002 in Pathology, Queen’s University, Canada. His MSc was under the supervision of Professor Alan Giles on the clearance and biosynthesis of VWF during disseminated intravascular coagulation, and his Ph.D. was under the supervision of Professor Peter Greer on the regulation of hematopoiesis by the tyrosine kinases Fps and Fer. In 2002 he joined the laboratory of Professor Steve Watson in Pharmacology, University of Oxford, the UK as a postdoctoral researcher, characterizing novel receptors and signaling pathways regulating platelet function. In 2003 he was appointed to a 5-year research position in the Birmingham Platelet Group, Physiology, University of Birmingham, the UK, which allowed him to start developing his research interests on platelet tyrosine phosphatases.
He was awarded a BHF Intermediate Basic Science Research Fellowship in 2009 and a Senior Fellowship in 2013 investigating the inhibitory receptor G6b-B and tyrosine phosphatases Shp1 and Shp2. He was promoted to Chair in Cellular Haemostasis in the College of Medical and Dental Sciences, the University of Birmingham in 2013. In 2019 he was appointed Director of Research at Etablissement Français du Sang / Inserm UMR S1255 Strasbourg, France under the Directorship of Dr. Christian Gachet. In his research, Dr. Senis takes a multidisciplinary approach investigating how tyrosine phosphatases work in conjunction with tyrosine kinases to regulate platelet activation, with the overall objective of identifying novel anti-thrombotic drug targets.