William T. Pu MD

William Pu, MD, is the director of Basic and Translational Cardiovascular Research in the Department of Cardiology at Boston Children’s Hospital and the Aldo R. Professor of Pediatrics at Harvard Medical School. Dr. Pu has broad expertise in cardiac biology that includes cardiac development, heart failure, cardiac regeneration, and in vitro cardiac disease modeling. His lab has made fundamental discoveries in gene regulation in developing and diseased hearts, particularly in the area of transcriptional regulation. Many of these discoveries are the result of innovative approaches to studying heart development and disease, often involving multidisciplinary collaborations that draw on advances in other fields.

His lab is currently engaged in research projects on the genetic causes of inherited heart diseases and gene therapy for Barth Syndrome and CPVT. Dr. Pu completed his combined BS-MS degree at Yale University and obtained his MD degree from the Harvard Medical School/MIT Science and Technology Program in 1993. He trained in pediatrics and pediatric cardiology at Boston Children’s Hospital. He received his training in basic research in the laboratories of Kevin Struhl, David Clapham, and Seigo Izumo. He established an independent research lab at Boston Children’s in 2004.