Dr. Wenyi Wei received his B.A. degree from Shandong University in 1993 and then obtained his M.S. training at the Chinese Academy of Science from 1993 to 1996. Afterward, Dr. Wei received his Ph.D. training in the MCB department at Brown University and his postdoctoral training in the laboratory of Dr. William Kaelin, Jr. at DFCI, Harvard Medical School. Dr. Wei became independent in October 2006 in the Department of Pathology at Beth Israel Deaconess Medical Center, Harvard Medical School.
The major focus of the WEI laboratory is aimed at understanding how APC and SCF activities contribute to cell cycle regulation and subsequent tumor formation. To achieve these goals, the lab will use multidisciplinary approaches including biochemical and genetic analysis. In the long term, we hope that a better understanding of the multilayer regulation of the delicate proteolysis pathways will lead us to the design of more efficient intervention strategies to combat cancer, cardiovascular disorders, and other human diseases.
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