Tsvee Lapidot PhD

Prof. Tsvee Lapidot from the Weizmann Institute received the 2019 Rappaport prize for a senior researcher for his studies on the topics of normal and leukemic human stem cells, their identification, function, and regulation. Tsvee developed functional pre-clinical transplantation assays for normal and leukemic human stem cells in transplanted immune-deficient mice. These models are based on clinical bone marrow transplantation protocols. The transplanted immune-deficient mice do not reject the human stem cells, providing in vivo assays for identification and characterization of human blood-forming stem cells, their function, and regulation.