Thomas Brabletz MD

Thomas Brabletz is Professor for Molecular Oncology and Chairman of the Dept. of Experimental Medicine, University Erlangen, Germany. Focusing on malignant cancer progression, in particular, mechanisms of invasion and metastasis, he aims to integrate basic and clinically relevant cancer research. He proposed a concept of transient rounds of EMT and MET, resulting in aberrant cellular plasticity and the generation of ‘Migrating cancer stem cells’ as the driving force of metastasis. Currently, his major interests are in uncovering underlying mechanisms, such as feedback loops between EMT-inducers, oncogenic pathways and microRNAs, as the basis for novel therapeutic strategies to fight cancer metastasis.