Sylvain Ladame PhD

Dr Sylvain Ladame received his Ph.D. in Chemistry of biomolecules in 2001 from the University of Toulouse, France. He then worked for five years in the group of Pr Shankar Balasubramanian at the Chemistry Department of the University of Cambridge (U.K.) where he developed an interest in the molecular recognition of nucleic acids. In 2006, he joined the CNRS and the Institut de Science et d'Ingénierie Supramoléculaires (ISIS) at the University of Strasbourg, France, where he created the junior research laboratory of Chemistry of Biomolecules. In July 2010, he was appointed Lecturer in Biosensor Development at the Department of Bioengineering of Imperial College.

Dr. Ladame has been working in the field of nucleic acid ligands and probes for almost ten years and has published over 30 papers in this field. His current interests deal with the engineering of small molecules and proteins for sensing and targeting nucleic acid structures in vivo. Dr Ladame's group aims to develop original chemical and biochemical tools to explore key biological processes (e.g. DNA transcription, DNA damage repair mechanisms), focusing on the identification of new therapeutic targets and disease-related biomarkers.