Susan S. Smyth MD, PhD, FACC

Dr. Smyth is a physician scientist who combines clinical practice in cardiology with NIH-, VA-, and industry-funded research focused on the interplay between inflammation and thrombosis in vascular biology. Her research seeks to define the contribution of extracellular mediators and blood and vascular cell-surface signaling receptors to test the pathways in clinical studies in humans.

Her work has resulted in novel mechanistic insight into thromboinflammatory pathways and the generation of unique reagents, preclinical models, technology, and new therapeutic strategies for vascular diseases. Recent studies investigate pathways for production, metabolism, and biologic effects of lysophospholipid mediators in cardiovascular health and disease.

Her clinical interests are in arterial and venous thrombosis, and she leads an enterprise-wide effort in thrombosis prevention and management. She has authored more than 150 publications and contributed to over a dozen textbooks.