Sudhanshu Shukla MSc, PhD

Dr. Shukla completed his M.Sc. (2001) from Banaras Hindu University, Varanasi, India after which he joined the School of Life Sciences, Jawaharlal Nehru University, New Delhi for his Ph.D. degree where he worked to understand the drug efflux mechanism mediated by multidrug transporter Cdr1p (Candida Resistance Protein 1) of pathogenic fungus Candida albicans. He worked as a postdoctoral visiting fellow (2008-14) at the National Institutes of Health, USA. After completing of his postdoctoral training at NIH, he joined Amity University of Haryana (AUH), Gurgaon as an Assistant Professor in 2015.

Currently, Dr. Shukla's research interests include understanding the drug efflux mechanisms shown by various multi-drug transporters in the pathogenic fungus C. albicans. This study is important in the context of fungal infections due to increased over-expressions of ABC transporters and MFS transporters owing to the development of multi-drug resistance, which limits the actions of various therapeutic azoles.

Shukla is also interested in finding novel therapeutic targets responsible for minimizing radio therapy-induced neurotoxicity, which is one of the effective treatments for intracranial tumors. In another study, he is studying as how the trafficking of various death receptors is regulated in cancerous cells leading to altered apoptosis in response to treatments of various chemotherapeutic agents.