Stephen J. Shuttleworth BSc, PhD, FRSC
Biochemistry and Molecular Genetics
Oxfordshire, England, United Kingdom
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Stephen joined Karus as CSO in 2008, and is the founding scientist of the company’s PI3K-p110β/δ and HDAC6 programs. Over the last 21 years, he has established a strong track record in R&D management, and in the design and development of molecular-targeted therapeutics for cancer, immune-inflammation and metabolic diseases.
Prior to Karus, Stephen held senior positions in UK and North American biotech, notably at Celltech-Chiroscience (UK), BiochemPharma-Shire (Quebec), Tularik-Amgen (California), CRUK, and Piramed (UK) where he directed the PI3K-p110α and p110δ programs, designing and leading the preclinical development of GDC-0941 (Pictilisib), currently in Phase II cancer trials, under the auspices of Roche, who acquired Piramed in 2008.
Prior to Karus, Stephen held senior positions in UK and North American biotech, notably at Celltech-Chiroscience (UK), BiochemPharma-Shire (Quebec), Tularik-Amgen (California), CRUK, and Piramed (UK) where he directed the PI3K-p110α and p110δ programs, designing and leading the preclinical development of GDC-0941 (Pictilisib), currently in Phase II cancer trials, under the auspices of Roche, who acquired Piramed in 2008.
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