Shinghua Ding PhD

Ischemic stroke is a leading neural disorder that causes brain damage and human death, and has a major impact on public health. My main research interest is to understand mechanisms by which ischemic stroke cause brain damage. My research focuses on two distinct but related areas: 1) Glial function and glia-neuron interactions in health and ischemic stroke; 2) Neural degeneration/regeneration, and brain recovery after ischemic stroke. We use both in vivo mouse and in vitro primary cultured cell ischemic models. Multiple approaches including molecular biology, transgenic mice, in vivo two-photon (2-P) microscopy, electrophysiology, biochemistry, cell death and proliferating assays, and immunocytochemistry are integrated in our research.