Sendurai Mani PhD

Sendurai A. Mani is a Professor in the Department of Pathology and Laboratory Medicine at Brown University. He is also the Associate Director of Translational Oncology at Brown University Legorreta Cancer Center. Dr. Mani earned a Ph.D. from The Indian Institute of Science, Bangalore, India, and then did postdoctoral work with Dr. Robert A. Weinberg at the Whitehead Institute/Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA. He then joined the University of Texas MD Anderson Cancer Center, Houston, Texas as an Assistant Professor in December of 2007 and has been promoted to Associate Professor with tenure in 2013. In late 2022, Dr. Mani joined Brown University Legorreta Cancer Center as a professor and Associate Director of Translational Oncology. Dr. Mani has received numerous prizes and awards for his research, including the Jimmy V Foundation’s V-Scholar Award and The American Cancer Society Research Scholar Award. Dr. Mani’s original finding demonstrating that cancer cells acquire stem cell properties by activating latent embryonic epithelial-mesenchymal transition (EMT) program provided the foundation and explanation for the presence of plasticity within the tumor as well as the development of resistance to various treatments.