Speaker Profile
Sarosh R. Irani

Sarosh R. Irani FRCP, DPhil, FEAN

Neurology
Jacksonville, Florida, United States of America

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Dr. Sarosh R. Irani graduated in medicine (BMBCh) from the University of Oxford, UK, and completed his internal medicine training in Oxford and London between 2003 and 2006. He subsequently earned a DPhil (PhD) in Clinical Neurology from the University of Oxford and completed residency training in neurology in London and Oxford. He then undertook a Fulbright Fellowship in multiple sclerosis and autoimmune neurology at the University of California, San Francisco (UCSF), USA.

Since 2014, he has practiced as a Consultant Neurologist in Oxford, caring for patients with a broad range of neurological disorders, with a particular focus on autoimmune neurological diseases. He founded the Oxford Autoimmune Neurology Clinic and was promoted to Professor of Autoimmune Neurology at the University of Oxford in 2021. In 2023, he joined Mayo Clinic Florida as Professor of Neurology and Neurosciences.

He has extensive expertise in the diagnosis and management of autoimmune neurological disorders, including autoimmune encephalitis, neuromyelitis optica, stiff-person syndrome, and paraneoplastic neurological syndromes. He was instrumental in the discovery of LGI1 and CASPR2 antibodies and has cared for more than 300 patients with LGI1, CASPR2, NMDA, AQP4, MOG, and GABA receptor antibodies, as well as seronegative forms of encephalitis and neuromyelitis optica. He is recognized as one of the world's leading clinicians in this field.

In addition to his clinical work, he serves as an advisor to the Encephalitis Society and the Autoimmune Encephalitis Alliance, two major organizations dedicated to patient support and advocacy. He also leads an internationally recognized research group that has made several landmark discoveries, including the identification of LGI1 and CASPR2 antibodies and characterization of their associated clinical syndromes. He has authored more than 200 scientific publications on autoimmune neurological diseases and has received numerous international awards in recognition of his pioneering clinical and research contributions.

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