Sandra Smieszek PhD

Sandra P Smieszek is leading several genetic disorders in the CNS domain and other rare complex phenotypes. She just completed her Postdoctoral training in the Department of Epidemiology and Biostatistics working for Dr. William Bush and Dr. Jonathan Haines. She completed her PhD at the Centre for Systems and Synthetic Biology at Royal Holloway, the University of London under the supervision of Dr. Paul Devlin. Her research focuses on translating biomedical big data with the aim of elucidating the human genotype-phenotype associations. Specifically, her research focuses on delineating the genetic underpinnings of complex traits and disorders with an emphasis on Alzheimer’s disease, HIV-associated phenotype, and autism spectrum disorders among others. Her particular interests include the application of concepts within the domains of translational bioinformatics, machine learning, systems biology, and network inference to elucidate the complex interactions giving rise to observed phenotypes. Her previous research was in the domain of the circadian clock working on various types of omics time series data. She is a Member of the International Society for Computational Biology, American Society of Human Genetics, and Royal Society of Biology with an avid interest in synthetic genomics, genetic engineering, and science policy.