Roland L. Dunbrack, Jr PhD

Dr. Roland L. Dunbrack, Jr. and his research group at the Fox Chase Cancer Center concentrate on research in computational structural biology, including homology modeling, fold recognition, molecular dynamics simulations, statistical analysis of the PDB, and bioinformatics. In developing these methods, they use methods from various areas of mathematics and computer science, including Bayesian statistics and computational geometry. The Dunbrack group places an emphasis on large-scale benchmarking of new methods and comparison with existing methods. They are also interested in applying comparative modeling to important problems in various areas of biology. Areas of particular interest include DNA repair, proteases and other peptide-binding protein families, and membrane proteins.