Robert Sims BS, PhD

Dr. Sims joined Constellation Pharmaceuticals in 2008 as a founding scientist. With nearly 20 years of experience in chromatin biology and transcription, Dr. Sims helped establish Constellation’s industry-leading epigenetics platform. Dr. Sims led the discovery and translational efforts for CPI-0610, a novel BET bromodomain inhibitor currently in phase 1 clinical development for hematologic malignancies.

His team’s notable work, along with others in the field, includes the discovery that BET bromodomain inhibition silences the expression of the MYC oncogene. Dr. Sims has authored more than 30 scientific publications in top-tier journals, including Science, Nature, and Cell. He received his Ph.D. in Cellular and Molecular Biology from the University of Texas at Austin and completed his postdoctoral training at UMDNJ-Robert Wood Johnson Medical School and the New York University School of Medicine.