Robert Roskoski Jr studied chemistry at Bowling Green State University, receiving a Bachelor of Science degree in 1961. He received a Medical Doctor's degree in 1964 and a Doctor of Philosophy degree in 1968 from the University of Chicago. His doctoral adviser was Donald F. Steiner, the discoverer of proinsulin.[2] Roskoski served in the medical corps of the United States Air Force from 1966 to 1969, where he became a captain. Later, He became a senior investigator at the U.S. Air Force School of Aerospace Medicine at Brooks Air Force Base in San Antonio. He subsequently performed postdoctoral studies at Rockefeller University under the tutelage of Fritz Lipmann from 1969 to 1972.
Roskoski did research on the classification of small molecule protein kinase inhibitors that are used in the treatment of several cancers and he also developed the gold standard procedure for the measurement of protein kinase enzyme activity. His research interests include protein kinase structure and function, cancer chemotherapy, and signal transduction.
He studied protein kinase structure and function and signal transduction.[7][8] He also founded the Blue Ridge Institute for Medical Research in Horse Shoe, North Carolina in 2006. Research at the institute focuses on protein kinase inhibitors approved by the US Food and Drug Administration and monitoring extramural National Institutes of Health grant support.