Robert Burton was an undergraduate at Melbourne and Newcastle Universities, Australia. His postgraduate medical, surgical and scientific training was at the Royal Melbourne and Royal Children's Hospitals, the University of Melbourne and the Walter & Eliza Hall Institute of Medical Research (Australia), Greenlane Hospital (New Zealand), Harvard University/Massachusetts General Hospital (USA), specializing in cardiovascular/transplant surgery and cancer immunology.
From 1977-1980 he was a Research Fellow in Surgery and in 1981 Assistant Professor of Surgery at Harvard University. For his research on cancer, in 1980 he was awarded the inaugural John Mitchell Crouch Fellowship of the Royal Australasian College of Surgeons, and in 1981 the Colleges’ Alan Newton Prize.
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