Dr. Robert Krance is the Director of the Pediatric Bone Marrow Transplant (BMT)/Stem Cell Transplant Program at Texas Children’s Hospital. The clinical program, one of the most active in the country, treats patients with various hematologic, oncologic, immunologic and genetic disorders. Dr. Krance coordinates the clinical activities of the cell and gene therapy and the pediatric bone marrow transplant programs. Current initiatives focus on the development of transplantation using alternative donors and less than fully HLA matched related donors. Investigations are under way into the use of antibodies directed against hematopoietic cells and methods of stem cell purification. In collaboration with other investigators in the Center for Cell and Gene Therapy (CAGT), new cell based approaches are being conducted hopefully to diminish the impact of viral infection post transplantation.
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