Ravindra Gupta PhD

Professor Ravindra Gupta is member of AHRI Faculty and a Professor in University College London’s (UCL) Division of Infection & Immunity. He initially trained as a clinical infectious diseases physician and went on to do a PhD at UCL, where he examined the epidemiology and virology of HIV drug resistance in sub Saharan Africa and the interplay between the restriction factor tetherin and the HIV gene Vpu. Most of his work since has focussed on antiviral therapy for treatment of HIV, and he has led a number of studies, both clinical and in vitro, aimed at addressing the global emerging threat of drug resistant HIV. Ravi also leads an active basic lab science programme at UCL, working on the cellular biology of retroviruses.

This work complements his research into drug resistance by expanding our knowledge of how viruses manipulate the host environment in order to persist; this will inevitably impact response to drugs and the search for a cure. His programme of work is informed by clinical work as an infectious diseases physician in London where he has been able to study unique individuals with HIV in order to better understand viral reservoirs and immune control of HIV. Excitingly, he is currently conducting a study in collaboration with Imperial College aiming to demonstrate the world’s second HIV cure by stem cell transplantation.