Peter G. Wells PharmD

Peter G. Wells research is directed towards understanding the molecular and biochemical mechanisms resulting in such pathological sequelae, and the environmental and genetic determinants of individual susceptibility. A number of spontaneous and drug-induced diseases are explored in human subjects and in animal models, including liver and neurodegenerative diseases, birth defects, developmental deficits in CNS function and cancer. Relevant genes, proteins/enzymes and molecular target damage are assessed using a combination of chemical, biochemical and molecular biological techniques. To optimize interpretation of the results, in vivo studies are combined with a variety of in vitro approaches, including embryo and cell culture, as well as studies in subcellular fractions and at the molecular level.