Speaker Profile
Paul M. Scola

Paul M. Scola PhD

Biochemistry and Molecular Genetics
Cambridge, Massachusetts, United States of America

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Dr. Scola received his Ph.D. in organic chemistry from The Pennsylvania State University where he conducted research under the guidance of Professor Steven Weinreb. He then assumed a postdoctoral position at Harvard University under the tutelage of Professor Yoshito Kishi. Paul joined Bristol-Myers Squibb in 1992, where he is currently a Director in the department of Discovery Chemistry and Molecular Technologies. The focus of Paul’s research efforts includes the discovery of small molecule antiviral agents for the treatment of hepatitis C virus (HCV) infection. As part of that effort, Paul had the privilege of co-chairing the HCV NS3 protease inhibitor team which discovered BMS-650032 (asunaprevir), an approved treatment for HCV that is administered as a dual cocktail with BMS’ daclatasvir. More recently, Paul has co-led full-phase discovery teams in Immuno-Oncology. An important outcome of the team’s effort was the discovery of BMS-986189, a macrocyclic peptide that is a potent inhibitor of PD-L1 and has progressed to the clinical stage.

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