Paul Axelsen MD

Dr. Paul Axelsen is a Professor in the Departments of Pharmacology, Biochemistry and Biophysics, Medicine, and Infectious Diseases Section at the University of Pennsylvania School of Medicine. He received a medical degree from the Mayo Medical School. He is board certified in Infectious Diseases and Internal Medicine.

The Axelsen laboratory is focused on the pathogenesis of Alzheimer's disease, particularly in the roles of oxidative stress and protein-lipid interactions. A variety of whole-animal models and in vitro systems are used, as well as a large repository of human brain samples. The laboratory has developed novel isotope-based techniques for characterizing oxidative stress in the brain using mass spectrometry and various forms of optical spectroscopy, including infrared, fluorescence, and internal reflection spectroscopy.