Nicholas Papadopoulas PhD

Dr. Nickolas Papadopoulos is a professor of oncology and pathology at the Johns Hopkins University School of Medicine. His research focuses on cancer biology, genetics, and diagnostics. Dr. Papadopoulos is internationally known as a co‐discoverer of the genetic basis of the predisposition to hereditary nonpolyposis colon cancer (HNPCC), one of the most common hereditary forms of cancer, earlier in his career. He was part of the interdisciplinary team that was the first to sequence all of the protein-coding genes, determine genetic alterations, and construct expression profiles of four common tumor types. Later he was involved in the identification of genetic alterations that drive tumorigenesis in multiple tumor types. His noteworthy discoveries include the identification of novel mutations in chromatin remodeling genes in ovarian clear cell carcinomas and pancreatic neuroendocrine tumors.

Dr. Papadopoulos received his B.S. from the Aristotelian University of Thessaloniki in Greece. He earned his M.S. in biology at the University of Houston and his Ph.D. in biomedical sciences at the University of Texas Health Science Center at Houston. He completed a Fogerty Fellowship at the National Institute on Aging and a postdoctoral fellowship in oncology at the Johns Hopkins University School of Medicine. Dr. Papadopoulos joined the Johns Hopkins faculty in 2005.