Nello Mainolfi BSc, PhD

Nello Mainolfi PhD is the founder and CTO of Kymera Therapeutics LLC, the Cambridge(MA)-based biotech company pioneering targeted-protein degradation as a transformative new approach to creating breakthrough medicines. Nello, born in Napoli (Italy), has received his PhD in Chemistry from Imperial College, University of London and has continued postdoctoral training at The Scripps Research Institute in California. He then started his professional career at the Novartis Institute for Biomedical Research in Cambridge, MA where he advanced several programs from research into preclinical and clinical development.

While at Novartis he also championed new technologies such as using fragment-based drug discovery as a core strategy to deliver multiple development candidates. Nello is also Entrepreneur-in-Resident at Atlas Venture, a Cambridge based VC firm focused on investing in early-stage biotech. Nello is married to Paola Castaldi (also a scientist-manager at AstraZeneca) and father of 2. He enjoys running and sailing in his spare time.