Neal S. Young MD

Dr. Young’s research is focused on bone marrow failure human diseases that result in a failure to produce blood cells, i.e. aplastic anemia. His comprehensive bedside-to-bench approach begins with enrolling hundreds of patients per year in the largest bone marrow failure clinic in the world. His laboratory uses a variety of approaches to analyze these patient samples for clues to disease etiology, which then inform work in animal models. His research has taken several directions including immune-mediated pathology, the genetics of bone marrow failure, and viruses that provoke the abnormal immune response or directly kill hematopoietic stem cells.

Neal S. Young, M.D., joined the National Heart, Lung, and Blood Institute (NHLBI) in 1981. He is Chief of the Institute's Intramural Research Hematology Branch. Dr. Young's research interests are in human hematopoiesis, aplastic anemia and the pathogenesis and treatment of bone marrow failure; parvoviruses, hepatitis viruses, immune response to virus infection, apoptosis, interferon, cytokines, and other interleukins, and the mechanisms of genomic instability. His research includes direct patient care and clinical protocols for the treatment of bone marrrow failure; basic science laboratory experiments involving normal and abnormal blood cell production; and epidemiologic studies of aplastic anemia.

Dr. Young received an M.D. in 1971 from the Johns Hopkins School of Medicine in Baltimore, MD. He received an A.B. cum laude from Harvard College in Boston, MA in 1967. He did post-graduate medical training at Massachusetts General Hospital and Barnes Hospital at Washington University in St. Louis, MO.

Dr. Young has authored 270 original scientific and medical articles in peer reviewed journals and more than 120 reviews and chapters. He also is author or editor of 10 medical and scientific books. including a new textbook of hematology. He is co-inventor on 7 patents concerning B19 parvovirus. Dr. Young is a member of the American Society for Clinical Investigation, the American Association of Physicians, the American Federation for Clinical Research, the American Society of Hematology, and the International Society for Experimental Hematology. Dr. Young also is a Master of the American College of Physicians.